%0杂志文章%@ 1438-8871 %I JMIR出版物%V 24%卡塔尔世界杯8强波胆分析 N 9% P e37848 %T中国大陆女大学生人乳头瘤病毒预防接种网络教育计划:信息-动机-行为技能模型在聚类随机试验中的应用% a斯,苏明宇% a,蒋晓友% a,王宇% a,张文军% a,顾曦% a,马晓芬% a,李莉% a,张静% a,任绍凯% a,刘泽芳% a,乔远丽% a,有林%+中国医学科学院北京协和医学院人口医学与公共卫生学院,北京市东城区东丹三条5号,100730,86 10 65256070,suxiaoyou@hotmail.com %K人乳头瘤病毒疫苗接种%K网络教育%K信息-动机-行为技能模型%K女大学生%K中国%D 2022 %7 30.9.2022 %9原论文%J J医学互联网Res %G英语%X背景:近20年确诊宫颈癌患者以年轻女性为主。人类乳头瘤病毒(HPV)疫苗接种是预防HPV感染和子宫颈癌的最根本方法。然而,中国大陆大部分女大学生尚未接种疫苗,相关知识有限。通过互联网提供的基于理论的教育是在这一人群中推广HPV疫苗接种的一种潜在的可行和有用的方式。目的:这项为期3个月的随访研究旨在确定基于信息-动机-行为技能(IMB)模型的在线干预的可行性和有效性,以提高女大学生对HPV疫苗接种的认识和意愿。方法:采用聚类随机试验设计,针对中国大陆女大学生开展为期7天的在线HPV教育项目。招聘和问卷调查在网上进行,没有面对面的接触。采用SPSS 23.0进行统计分析。 The chi-square test and t test were used to compare differences in qualitative and continuous variables between intervention and control groups. The generalized estimating equation was used to test the effectiveness of the intervention with a consideration of the time factor. Results: Among 3867 participants, 102 had been vaccinated against HPV before the study (vaccination rate of 2.6%). A total of 3484 participants were followed up after the baseline survey, with no statistical difference in the loss rate between the intervention and control groups during the intervention and follow-up periods. At different follow-up time points, HPV-related knowledge, and the motivation, behavioral skills, and willingness regarding HPV vaccination were higher in the intervention group than in the control group. HPV-related knowledge was statistically different between the 2 groups, while the motivation, behavioral skills, and willingness regarding HPV vaccination only showed statistical differences right after the intervention, reaching a peak right after the intervention and then gradually reducing over time. Furthermore, there was no statistical difference in the HPV vaccination rate between the 2 groups. Conclusions: IMB model–based online education could be a promising way to increase the HPV vaccination rate and reduce the burden of HPV infection and cervical cancer among high-risk female college students in China. Trial Registration: Chinese Clinical Trial Registry ChiCTR1900025476; http://www.chictr.org.cn/showprojen.aspx? proj=42672 International Registered Report Identifier (IRRID): RR2-DOI:10.1186/s12889-019-7903-x %M 36178723 %R 10.2196/37848 %U //www.mybigtv.com/2022/9/e37848 %U https://doi.org/10.2196/37848 %U http://www.ncbi.nlm.nih.gov/pubmed/36178723
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