%0杂志文章%@ 1438-8871 %I JMIR出版物%V 22%卡塔尔世界杯8强波胆分析 N 4% P e15819 %T使用在线个人健康信息减少纤维肌痛影响:纵向观察研究%A Collinge,William %A Soltysik,Robert %A Yarnold,Paul %+ Collinge and Associates, Inc, 3480 Kincaid Street, Eugene, OR, 97405-0000, United States, 1 5416323502, william@collinge.org %K纤维肌痛%K纤维肌痛影响%K健康信息%K预测分析%K症状减轻%K功能状态%K个性化药物%K健康日记%D 2020 %7 7.4.2020 %9原始论文%J J Med Internet Res %G英文%X背景:个人健康信息学有潜力帮助患者发现影响结果的个性化健康管理策略。纤维肌痛(FM)是一种复杂的慢性疾病，需要个性化的治疗策略，可以通过个人健康信息数据的分析来提供信息。开发了一个具有动态反馈的在线健康日记计划，以帮助FM患者确定预测其个人结果的症状管理策略，并发现使用该计划可降低症状水平。目的:本研究的目的是通过标准化评估工具纤维肌痛影响问卷(FIQ)的分数来确定项目使用和FM功能影响之间的纵向关联。方法:参与者自认为被诊断为FM，并通过在线FM宣传网站招募。参与者使用在线健康日记程序(“SMARTLog”)报告症状等级、行为和使用的管理策略。基于对一段时间内累积数据的单主题分析，自动反馈程序随后提供个性化的建议(“SMARTProfile”)。程序使用的指标包括累计完成的smartlog数量和接收的SMARTProfiles数量。 Participants included in this analysis met a priori criteria of sufficient program use to generate SMARTProfiles (ie, ≥22 SMARTLogs completed). Users completed the FIQ at baseline and again each subsequent month of program use as follow-up data for analysis. Kendall tau-b, a nonparametric statistic that measures both the strength and direction of an ordinal association between two repeated measured variables, was computed between all included FIQ scores and both indices of program use for each subject at the time of each completed FIQ. Results: A total of 76 users met the a priori use criteria. The mean baseline FIQ score was 61.6 (SD 14.7). There were 342 FIQ scores generated for longitudinal analysis via Kendall tau-b. Statistically significant inverse associations were found over time between FIQ scores and (1) the cumulative number of SMARTLogs completed (tau-b=–0.135, P<.001); and (2) the cumulative number of SMARTProfiles received (tau-b=–0.133, P<.001). Users who completed 61 or more SMARTLogs had mean follow-up scores of 49.9 (n=25, 33% of the sample), an 18.9% drop in FM impact. Users who generated 11 or more new SMARTProfiles had mean follow-up scores of 51.8 (n=23, 30% of the sample), a 15.9% drop. Conclusions: Significant inverse associations were found between FIQ scores and both indices of program use, with FIQ scores declining as use increased. Based on established criteria for rating FM severity, the top one-third of users in terms of use had clinically significant reductions from “severe” to “moderate” FM impact. These findings underscore the value of self-management interventions with low burden, high usability, and high perceived relevance to the user. Trial Registration: ClinicalTrials.gov NCT02515552; https://clinicaltrials.gov/ct2/show/NCT02515552 %M 32131045 %R 10.2196/15819 %U //www.mybigtv.com/2020/4/e15819 %U https://doi.org/10.2196/15819 %U http://www.ncbi.nlm.nih.gov/pubmed/32131045