@ 1438- 8871% I Gunther Eysenbach对不寻求治疗的成年重度饮酒者进行基于互联网的简短个性化反馈干预:随机对照试验%A汉森，安德斯·布尔德尔·戈特利布%A贝克尔，乌尔里克%A尼尔森，Anette Søgaard %A grb æk,Morten %A托尔斯特鲁普，Janne Schurmann %A Thygesen,Lau Caspar %+南丹麦大学健康科学学院国家公共卫生研究所，Øster Farimagsgade 5 A, 2楼，哥本哈根，1353，丹麦，45 6550 7777 ext 7729，ago@niph.dk %K基于互联网的个性化反馈%K规范反馈%K酒精%K重度饮酒%K成人%K基于互联网的个性化简短建议，简短干预%D 2012 %7 30.07.2012 %9原始论文%J J医学互联网Res %G英语%X背景:基于互联网的重度饮酒者干预显示出良好的效果，但现有研究的特点是很少对非学生成人人群进行研究，很少与适当的对照组进行比较。目的:测试在不寻求治疗的重度饮酒者中，基于互联网的全自动个性化简短反馈干预和基于互联网的全自动个性化简短建议干预是否会导致酒精摄入量的减少。方法:我们在重度饮酒者的一般人群样本中进行了一项三组平行随机对照试验。54157名参与者(平均年龄58岁)接受了重度饮酒筛查。在3418名女性每周饮酒量超过14杯、男性超过21杯的参与者中，1380人(619名女性)同意参加试验，并被随机分配到基于互联网的简短个性化反馈干预组(规范反馈，n = 476)、基于互联网的个性化简短建议干预组(n = 450)或非干预对照组(n = 454)。6个月和12个月后的随访分别包括所有组的871和1064名参与者。结果测量是自我报告的每周饮酒量。我们根据意向治疗原则分析数据。 To examine changes over time and to account for the multiple time measurements, we used a multilevel linear mixed model. To take attrition into account, we used multiple imputation to address missing data. Results: The intervention effect of the Internet-based brief personalized feedback intervention, determined as the mean additional difference in changes in alcohol consumption in the Internet-based brief personalized feedback intervention compared with the control group, was –1.8 drinks/week after 6 months and –1.4 drinks/week after 12 months; these effects were nonsignificant (95% confidence interval –4.0 to 0.3 at 6 months, –3.4 to 0.6 at 12 months). The intervention effect of the Internet-based personalized brief advice intervention was –0.5 drinks/week after 6 months and –1.2 drinks/week after 12 months; these effects were nonsignificant (95% confidence interval –2.7 to 1.6 at 6 months, –3.3 to 0.9 at 12 months). Conclusions: In this randomized controlled trial we found no evidence that an Internet-based brief personalized feedback intervention was effective in reducing drinking in an adult population of heavy drinkers. Trial registration: ClinicalTrials.gov NCT00751985; http://clinicaltrials.gov/ct2/show/NCT00751985 (Archived by WebCite at http://www.webcitation.org/68WCRLyaP) %M 22846542 %R 10.2196/jmir.1883 %U //www.mybigtv.com/2012/4/e98/ %U https://doi.org/10.2196/jmir.1883 %U http://www.ncbi.nlm.nih.gov/pubmed/22846542