I Gunther Eysenbach %V 14% N 1% P e31% T基于移动电话的心脏衰竭远程监护管理:A Seto,Emily A Leonard,Kevin J %A Cafazzo,Joseph A A Barnsley,Jan A Masino,Caterina A Ross,Heather全球电子健康创新中心，大学卫生网，TGH/RFE大厦，4楼，多伦多，M5G 2C4，加拿大，1 416 340 4800 ext 6409，emily.seto@uhn.on.ca %K心力衰竭%K远程医疗%K手机%K患者监测%K随机对照试验%D 2012 %7 16.02.2012 %9原始论文%J J医学互联网Res %G英文%X背景:以前的心脏衰竭管理远程监测试验报告的结果不一致，主要是由于不同的干预和研究设计。移动电话正变得无处不在和经济，但一个基于移动电话的远程监测系统的可行性和有效性尚未确定。目的:本试验的目的是研究基于手机的远程监测系统对心力衰竭管理和结果的影响。方法:从心功能门诊招募100例患者，随机分为远程监测组和对照组。远程监测组(N = 50)每天记录体重和血压读数，每周单导联心电图，并在6个月内通过手机回答日常症状问题。数据自动通过无线传输到手机，然后传输到数据服务器。指令被发送到患者的手机上，警报被发送到心脏病专家的手机上。结果:94例患者完成并返回基线问卷，84例患者返回研究后问卷。 About 70% of telemonitoring patients completed at least 80% of their possible daily readings. The change in quality of life from baseline to post-study, as measured with the Minnesota Living with Heart Failure Questionnaire, was significantly greater for the telemonitoring group compared to the control group (P = .05). A between-group analysis also found greater post-study self-care maintenance (measured with the Self-Care of Heart Failure Index) for the telemonitoring group (P = .03). Brain natriuretic peptide (BNP) levels, self-care management, and left ventricular ejection fraction (LVEF) improved significantly for both groups from baseline to post-study, but did not show a between-group difference. However, a subgroup within-group analysis using the data from the 63 patients who had attended the heart function clinic for more than 6 months revealed the telemonitoring group had significant improvements from baseline to post-study in BNP (decreased by 150 pg/mL, P = .02), LVEF (increased by 7.4%, P = .005) and self-care maintenance (increased by 7 points, P = .05) and management (increased by 14 points, P = .03), while the control group did not. No differences were found between the telemonitoring and control groups in terms of hospitalization, mortality, or emergency department visits, but the trial was underpowered to detect differences in these metrics. Conclusions: Our findings provide evidence of improved quality of life through improved self-care and clinical management from a mobile phone-based telemonitoring system. The use of the mobile phone-based system had high adherence and was feasible for patients, including the elderly and those with no experience with mobile phones. Trial Registration: ClinicalTrials.gov NCT00778986 %M 22356799 %R 10.2196/jmir.1909 %U //www.mybigtv.com/2012/1/e31/ %U https://doi.org/10.2196/jmir.1909 %U http://www.ncbi.nlm.nih.gov/pubmed/22356799