@文章{info:doi/10.2196/37848，作者=“思、明宇和苏、小优和江、于和王、文君和张、希和顾、小芬和马、李和李、静和张、邵凯和任少凯、泽芳和刘、元利和乔友林”，标题=“中国大陆女大学生人乳头瘤病毒疫苗接种网络教育项目:信息-动机-行为技能模型在聚类随机试验中的应用”，期刊=《J medical Internet Res》，年=“2022”，月=“9”，日=“30”，卷=“24”，数=“9”，页=“e37848”，关键词=“人乳头瘤病毒疫苗接种;网络教育;information-motivation-behavioral技能模型;女大学生;背景:近20年来确诊的宫颈癌患者以年轻女性为主。人类乳头瘤病毒(HPV)疫苗接种是预防HPV感染和子宫颈癌最根本的方法。而中国大陆大部分女大学生还没有接种过疫苗，相关知识有限。通过互联网提供的基于理论的教育是在这一人群中促进HPV疫苗接种的一种潜在的可获得和有用的方式。目的:这项为期3个月的随访研究旨在确定基于信息-动机-行为技能(IMB)模型的在线干预的可行性和有效性，以提高女大学生对HPV疫苗接种的意识和意愿。 Methods: A 7-day online HPV education program for female college students in mainland China was developed using a cluster randomized trial design. Recruitment and questionnaire surveys were performed online without face-to-face contact. SPSS 23.0 was used for statistical analysis. The chi-square test and t test were used to compare differences in qualitative and continuous variables between intervention and control groups. The generalized estimating equation was used to test the effectiveness of the intervention with a consideration of the time factor. Results: Among 3867 participants, 102 had been vaccinated against HPV before the study (vaccination rate of 2.6{\%}). A total of 3484 participants were followed up after the baseline survey, with no statistical difference in the loss rate between the intervention and control groups during the intervention and follow-up periods. At different follow-up time points, HPV-related knowledge, and the motivation, behavioral skills, and willingness regarding HPV vaccination were higher in the intervention group than in the control group. HPV-related knowledge was statistically different between the 2 groups, while the motivation, behavioral skills, and willingness regarding HPV vaccination only showed statistical differences right after the intervention, reaching a peak right after the intervention and then gradually reducing over time. Furthermore, there was no statistical difference in the HPV vaccination rate between the 2 groups. Conclusions: IMB model--based online education could be a promising way to increase the HPV vaccination rate and reduce the burden of HPV infection and cervical cancer among high-risk female college students in China. Trial Registration: Chinese Clinical Trial Registry ChiCTR1900025476; http://www.chictr.org.cn/showprojen.aspx? proj=42672 International Registered Report Identifier (IRRID): RR2-DOI:10.1186/s12889-019-7903-x ", issn="1438-8871", doi="10.2196/37848", url="//www.mybigtv.com/2022/9/e37848", url="https://doi.org/10.2196/37848", url="http://www.ncbi.nlm.nih.gov/pubmed/36178723" }