杂志文章%@ 2291-5222 %I JMIR Publicatio卡塔尔世界杯8强波胆分析ns %V 8% N 11% P 23123% T重度呼吸暂停-低通气睡眠阻塞性综合征肌功能治疗应用程序:随机对照试验%A O'Connor-Reina,Carlos %A Ignacio Garcia,Jose Maria %A Rodriguez Ruiz,Elisa %A Morillo Dominguez,Maria Del Carmen %A Ignacio Barrios,Victoria %A Baptista Jardin,Peter %A Casado Morente,Juan Carlos %A Garcia Iriarte,Maria Teresa %A Plaza,Guillermo %+ Quironsalud Marbella医院耳鼻喉科，Avda Severo Ochoa 22，西班牙马贝拉，34 952774200，carlos.oconnor@quironsalud.es %K肌功能治疗%K口咽运动%K mHealth %K睡眠呼吸暂停%K智能手机应用%K app %K睡眠%K治疗%K呼吸暂停%K随机试验%K疗效%D 2020 %7 9.11.2020 %9原论文%J JMIR mHealth Uhealth %G英文%X背景:肌功能治疗在治疗睡眠呼吸障碍方面已证明有效。我们评估了一种新的移动健康(mHealth)应用程序的临床使用，该应用程序使用智能手机教严重阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者进行口咽练习。目的:我们进行了一项随机试验，评估app在严重OSAHS患者中的效果。方法:40例重度OSAHS(呼吸暂停-缺氧指数[AHI]>30)患者前瞻性入选，随机分为干预组和对照组，干预组使用该应用程序90次。测量干预前后的人体测量指标、爱普沃斯嗜睡量表(0-24)、匹兹堡睡眠质量指数(0-21)、爱荷华口腔表现量表(IOPI)评分和氧饱和度指数。结果:干预后，28例患者存活。对照组未见明显变化;然而，干预组在大多数指标上都有显著改善。 AHI decreased by 53.4% from 44.7 (range 33.8-55.6) to 20.88 (14.02-27.7) events/hour (P<.001). The oxygen desaturation index decreased by 46.5% from 36.31 (27.19-43.43) to 19.4 (12.9-25.98) events/hour (P=.003). The IOPI maximum tongue score increased from 39.83 (35.32-45.2) to 59.06 (54.74-64.00) kPa (P<.001), and the IOPI maximum lip score increased from 27.89 (24.16-32.47) to 44.11 (39.5-48.8) kPa (P<.001). The AHI correlated significantly with IOPI tongue and lip improvements (Pearson correlation coefficient −0.56 and −0.46, respectively; both P<.001). The Epworth Sleepiness Scale score decreased from 10.33 (8.71-12.24) to 5.37 (3.45-7.28) in the app group (P<.001), but the Pittsburgh Sleep Quality Index did not change significantly. Conclusions: Orofacial exercises performed using an mHealth app reduced OSAHS severity and symptoms, and represent a promising treatment for OSAHS. Trial Registration: Spanish Registry of Clinical Studies AWGAPN-2019-01, ClinicalTrials.gov NCT04438785; https://clinicaltrials.gov/ct2/show/NCT04438785 %M 33093013 %R 10.2196/23123 %U http://mhealth.www.mybigtv.com/2020/11/e23123/ %U https://doi.org/10.2196/23123 %U http://www.ncbi.nlm.nih.gov/pubmed/33093013