基于沉浸式虚拟现实的认知干预，改善轻度认知障碍和轻度痴呆老年人的认知功卡塔尔世界杯8强波胆分析能、抑郁和感知压力:朱a，张凯燕，何琼瑶，黄炳伟，林美珍，李蓉，洪+福建省立医院护理科护理理论与实践研究中心，福州鼓楼区东街134号，350001,86 13705070219，leehong99@126.com %K认知干预%K痴呆%K沉浸式虚拟现实%K轻度认知障碍%K认知障碍%K虚拟现实%K VR %K老年患者%K可用性%K记忆%K压力%D 2022 %7 21.2.2022 %9原始论文%J JMIR严肃游戏%G英语%X背景:痴呆症的发病率每年都在增加，对个人、家庭和社会造成不同程度的不良影响。随着计算机信息技术的不断发展，认知干预也在不断发展。使用沉浸式虚拟现实(IVR)作为轻度认知障碍(MCI)和轻度痴呆(MD)的老年人的认知干预是有希望的，尽管只有少数研究关注它的使用。目的:开发中国虚拟超市(CVSM) IVR系统，为老年MCI和MD患者提供全面、个性化的认知干预方案。本研究旨在探讨基于CVSM的5周认知干预的可行性和临床效果。方法:从2020年8月到2021年1月，对31名患有MCI和MD的老年人进行了前测-后测研究设计。所有参与者都使用CVSM系统参加了为期5周的沉浸式虚拟认知训练计划。根据干预后进行的问卷调查，可行性评估为晕屏症状的发生率和严重程度以及参与者的满意度。临床疗效通过神经心理学评估进行评估，包括几种常用的认知功能、抑郁、感知压力和日常生活活动的测量。 Measurements were obtained at baseline and after the intervention period. Results: A total of 18 patients with MCI (mean age 82.94 [SD 5.44] years; 12 females) and 13 patients with MD (mean age 85.7 [SD 4.67] years, 10 females) participated in this pilot study. Both groups showed significant improvements in all cognitive function measurements (P<.001). The MD group had a significantly greater improvement in general cognitive function compared to the MCI group in Montreal Cognitive Assessment Scale, Symbol Digit Modalities Test, Shape Trail Test, and Auditory Verbal Learning Test. Furthermore, an intervention effect was observed in the improvement of perceived stress (P=.048 for MD group, P=.03 for MCI group ). Conclusions: The use of the CVSM system may be effective in enhancing the cognitive function of patients with MCI and MD, including general cognitive function, memory, executive function, and attention. IVR technology enriches cognitive intervention approaches and provides acceptable, professional, personalized, and interesting cognitive training for older adults with cognitive impairment. Trial Registration: ClinicalTrials ChiCTR2100043753; https://trialsearch.who.int/Trial2.aspx?TrialID=ChiCTR2100043753 %M 35188466 %R 10.2196/32117 %U https://games.www.mybigtv.com/2022/1/e32117 %U https://doi.org/10.2196/32117 %U http://www.ncbi.nlm.nih.gov/pubmed/35188466