@文章{信息:doi/10.2196/32625，作者=“Tenbult, Nicole和Kraal, Jos和Brouwers, Rutger和Spee, Ruud和Eijsbouts, Sabine和Kemps, Hareld”，标题=“坚持房颤和肥胖患者的多学科生活方式计划:可行性研究”，期刊=“JMIR Form Res”，年=“2022”，月=“Apr”，天=“29”，卷=“6”，数量=“4”，页=“e32625”，关键词=“心脏康复;心房颤动;肥胖;参与;完成;依从性;背景:心房颤动通常与肥胖有关。观察性研究表明，体重减轻与改善预后和降低房颤频率和严重程度有关。然而，尽管有这些好处，不坚持生活方式计划是很常见的。目的:在本研究中，我们评估了以房颤和肥胖患者的行为改变为重点的多学科生活方式计划的依从性和可行性。 Methods: Patients with atrial fibrillation and obesity participated in a 1-year goal-oriented cardiac rehabilitation program. After baseline assessment, the first 3 months included a cardiac rehabilitation intervention with 4 fixed modules: lifestyle counseling (with an advanced nurse practitioner), exercise training, dietary consultation, and psychosocial therapy; relaxation sessions were an additional optional treatment module. An advanced nurse practitioner monitored the personal lifestyle of each individual patient, with assessments and consultations at 3 months (ie, immediately after the intervention) and at the end of the year (ie, 9 months after the intervention). At each timepoint, level of physical activity, personal goals and progress, atrial fibrillation symptoms and frequency (Atrial Fibrillation Severity Scale), psychosocial stress (Generalized Anxiety Disorder--7), and depression (Patient Health Questionnaire--9) were assessed. The primary endpoints were adherence (defined as the number of visits attended as percentage of the number of planned visits) and completion rates of the cardiac rehabilitation intervention (defined as performing at least of 80{\%} of the prescribed sessions). In addition, we performed an exploratory analysis of effects of the cardiac rehabilitation program on weight and atrial fibrillation symptom frequency and severity. Results: Patients with atrial fibrillation and obesity (male: n=8; female: n=2; age: mean 57.2 years, SD 9.0; baseline weight: mean 107.2 kg, SD 11.8; baseline BMI: mean 32.4 kg/m2, SD 3.5) were recruited. Of the 10 participants, 8 participants completed the 3-month cardiac rehabilitation intervention, and 2 participants did not complete the cardiac rehabilitation intervention (both because of personal issues). Adherence to the fixed treatment modules was 95{\%} (mean 3.8 sessions attended out of mean 4 planned) for lifestyle counseling, 86{\%} (mean 15.2 sessions attended out of mean 17.6 planned) for physiotherapy sessions, 88{\%} (mean 3.7 sessions attended out of mean 4.1 planned) for dietician consultations, and 60{\%} (mean 0.6 sessions attended out of mean 1.0 planned) for psychosocial therapy; 70{\%} of participants (7/10) were referred to the optional relaxation sessions, for which adherence was 86{\%} (mean 2 sessions attended out of mean 2.4 planned). The frequency of atrial fibrillation symptoms was reduced immediately after the intervention (before: mean 35.6, SD 3.8; after: mean 31.2, SD 3.3), and this was sustained at 12 months (mean 24.8, SD 3.2). The severity of atrial fibrillation complaints immediately after the intervention (mean 20.0, SD 3.7) and at 12 months (mean 9.3, SD 3.6) were comparable to that at baseline (mean 16.6, SD 3.3). Conclusions: A 1-year multidisciplinary lifestyle program for obese patients with atrial fibrillation was found to be feasible, with high adherence and completion rates. Exploratory analysis revealed a sustained reduction in atrial fibrillation symptoms; however, these results remain to be confirmed in large-scale studies. ", issn="2561-326X", doi="10.2196/32625", url="https://formative.www.mybigtv.com/2022/4/e32625", url="https://doi.org/10.2196/32625", url="http://www.ncbi.nlm.nih.gov/pubmed/35486435" }