TY - JOUR AU - Puthusseryppady, Vaisakh AU - Morrissey, Sol AU - Aung, Min Hane AU - Coughlan, Gillian AU - Patel, Martyn AU - Hornberger, Michael PY - 2022 DA - 2022/4/21 TI -使用GPS跟踪调查阿尔茨海默病患者的户外导航模式:横断面研究乔- JMIR老化SP - e28222六世- 5 - 2 KW -阿尔茨海默病千瓦痴呆KW -空间定向障碍KW -迷失KW -户外导航KW -风险因素KW -环境KW - GPS跟踪KW -社区KW -手机AB -背景:空间定向障碍是最早的也是最痛苦的症状出现在阿尔茨海默病(AD)患者,会导致他们迷失在社区。虽然这是一个在世界范围内普遍存在的问题，并与各种负面后果有关，但很少有人知道AD患者的户外导航模式在多大程度上解释了为什么他们即使在熟悉的环境中也会出现空间定向障碍。目的:本研究旨在了解AD患者在不同情况下的户外导航模式(单独vs伴有;在研究过程中定向障碍和无定向障碍)，并调查AD患者在户外地标密度高、道路网络结构复杂(道路交叉口密度、交叉口复杂性和方向熵)的环境中导航时是否会出现空间定向障碍。方法:我们使用GPS跟踪和轨迹挖掘分析技术，调查了社区AD患者(n=15)和年龄匹配的健康对照组(n=18) 2周内的户外导航模式。在此，对于患者，记录在此跟踪期间发生的任何空间定向障碍行为。我们还使用空间缓冲方法来捕捉参与者在跟踪期间访问的环境中的室外地标密度和道路网络的特征。结果:AD患者在陪同下的户外导航模式与对照组相似;然而，当他们独处时，他们每天的外出次数显著减少(总外出次数:P<.001; day outings: P=.003; night outings: P<.001), lower time spent moving per outing (P=.001), lower total distance covered per outing (P=.009), lower walking distance per outing (P=.02), and lower mean distance from home per outing (P=.004). Our results did not identify any mobility risk factors for spatial disorientation. We also found that the environments visited by patients who experienced disorientation versus those who maintained their orientation during the tracking period did not significantly differ in outdoor landmark density (P=.60) or road network structure (road intersection density: P=.43; intersection complexity: P=.45; orientation entropy: P=.89). Conclusions: Our findings suggest that when alone, patients with AD restrict the spatial and temporal extent of their outdoor navigation in the community to successfully reduce their perceived risk of spatial disorientation. Implications of this work highlight the importance for future research to identify which of these individuals may be at an actual high risk for spatial disorientation as well as to explore the implementation of health care measures to help maintain a balance between patients’ right to safety and autonomy when making outings alone in the community. SN - 2561-7605 UR - https://aging.www.mybigtv.com/2022/2/e28222 UR - https://doi.org/10.2196/28222 UR - http://www.ncbi.nlm.nih.gov/pubmed/35451965 DO - 10.2196/28222 ID - info:doi/10.2196/28222 ER -