TY - JOUR AU - Hesseldal, Laura AU - Christensen, Jeanette Reffstrup AU - Olesen, Thomas Bastholm AU - Olsen, Michael Hecht AU - Jakobsen, Pernille Ravn AU - Laursen, Ditte Hjorth AU - Lauridsen, Jørgen Trankjær AU - Nielsen, Jesper Bo AU - s ø nderard, Jens AU - Brandt, Carl Joakim PY - 2022 DA - 2022/9/23 TI -以初级保健为基础的电子健康生活方式指导计划的长期减肥:随机对照试验乔- J地中海互联网Res SP - e39741六世- 24 - 9千瓦-肥胖KW -数字行为指导KW -健康行为改变千瓦互动建议KW -生活方式的改变KW -移动干预KW -病人接触KW -远程医疗KW -电子健康KW -数字健康KW -数字教练KW -减肥KW -指导KW -培训KW -订婚千瓦行为变化KW -糖尿病KW - 2型糖尿病KW - T2D AB -背景:肥胖患者长期减重可减少非传染性疾病的风险和进展。观察性研究表明，数字教练可以导致长期的体重减轻。目的:我们调查了与常规护理相比，eHealth生活方式指导项目是否对伴有或不伴有2型糖尿病的肥胖患者产生了显著的长期(12个月)体重减轻。方法:在丹麦50个城市进行的一项随机对照试验中，从2018年4月16日至2019年4月1日招募了340名伴有或不伴有2型糖尿病的肥胖患者，并通过自动计算机算法随机分为干预组(n=200)或对照组(n=140)。患者是通过全科医生、丹麦糖尿病组织和社交媒体招募的。数字指导干预包括最初的1小时面对面的动机访谈，然后是使用个人实时监控支持的行为改变技术的数字指导。主要结局是体重从基线到12个月的变化。结果:对200名参与者的数据进行了评估，其中干预组127人，对照组73人，他们完成了12个月的随访。 After 12 months, mean body weight and BMI were significantly reduced in both groups but significantly more so in the intervention group than the control group (–4.5 kg, 95% CI –5.6 to –3.4 vs –1.5 kg, 95% CI –2.7 to –0.2, respectively; P<.001; and –1.5 kg/m2, 95% CI –1.9 to –1.2 vs –0.5 kg/m2, 95% CI –0.9 to –0.1, respectively; P<.001). Hemoglobin A1c was significantly reduced in both the intervention (–6.0 mmol/mol, 95% CI –7.7 to –4.3) and control (–4.9 mmol/mol, 95% CI –7.4 to –2.4) groups, without a significant group difference (all P>.46). Conclusions: Compared to usual care, digital lifestyle coaching can induce significant weight loss for people living with obesity, both with and without type 2 diabetes, after 12 months. Trial Registration: ClinicalTrials.gov NCT03788915; https://clinicaltrials.gov/ct2/show/NCT03788915 SN - 1438-8871 UR - //www.mybigtv.com/2022/9/e39741 UR - https://doi.org/10.2196/39741 UR - http://www.ncbi.nlm.nih.gov/pubmed/36149735 DO - 10.2196/39741 ID - info:doi/10.2196/39741 ER -