TY - JOUR AU - Lindsäter, Elin AU - Axelsson, Erland AU - Salomonsson, Sigrid AU - Santoft, Fredrik AU - Ljótsson, Brjánn AU - Åkerstedt, Torbjörn AU - Lekander, Mats AU - Hedman-Lagerlöf, Erik PY - 2019 DA - 2019/09/13 TI -治疗师引导的基于网络的认知行为治疗压力相关障碍的成本-效果:一项随机对照试验的二次分析[J] Med Internet Res SP - e14675 VL - 21 IS - 9 KW -心理应激KW -适应障碍KW -疲惫障碍KW -认知行为治疗KW -成本效益KW - Internet AB -背景:压力相关障碍与显著的痛苦、功能损害和高社会成本相关。基于网络的认知行为疗法(ICBT)是一种很有前景的治疗压力相关疾病的方法，但迄今为止尚未进行健康经济评估。目的:本研究的目的是评估ICBT治疗以适应障碍(AD)或衰竭障碍(ED)形式出现的压力相关障碍患者的成本-效果和成本-效用。我们假设ICBT与等候名单对照组(WLC)相比，将以较低的净成本产生改善，从而使其具有成本效益。方法:健康经济数据与一项为期12周的ICBT随机对照试验相结合，其中100例患者被随机分为ICBT组(N= 50)和WLC组(N= 50)。对治疗前后的健康结果和成本进行了调查。我们计算了基于缓解率的增量成本-效果比(ICERs)和基于健康相关生活质量的增量成本-效用比(ICURs)。采用自举抽样来评估结果的不确定性。结果:ICER表明，与WLC相比，ICBT最有可能导致更高的缓解率，并且从治疗前到治疗后的成本降低幅度略大。 ICBT had a 60% probability of being cost-effective at a willingness to pay (WTP) of US $0 and a 96% probability of being cost-effective at a WTP of US $1000. The ICUR indicated that ICBT also led to improvements in quality of life at no net societal cost. Sensitivity analyses supported the robustness of our results. Conclusions: The results suggest that ICBT is a cost-effective treatment for patients suffering from AD or ED. Compared with no treatment, ICBT for these patients yields large effects at no or minimal societal net costs. Trial Registration: ClinicalTrials.gov NCT02540317; https://clinicaltrials.gov/ct2/show/NCT02540317 SN - 1438-8871 UR - //www.mybigtv.com/2019/9/e14675 UR - https://doi.org/10.2196/14675 UR - http://www.ncbi.nlm.nih.gov/pubmed/31586370 DO - 10.2196/14675 ID - info:doi/10.2196/14675 ER -