TY -非盟的花王Chi-Wen AU - Chen Ting-Yu AU - Cheng Shu-Meng AU -林,Wei-Shiang AU - Chang Yue-Cune PY - 2019 DA - 2019/12/5 TI -一个基于web的Self-Titration程序控制原发性高血压患者血压:随机对照试验乔- J地中海互联网Res SP - e15836六世- 21 - 12 KW -基于web的千瓦Self-Titration KW -血压KW -高血压KW - AB -背景:健康相关的生活质量高血压是心脏、血管和肾脏疾病死亡的主要原因。有效控制血压升高已被证明可以减少靶器官损伤。基于网络的自我滴定计划可能使患者能够控制自己的疾病，分享抗高血压剂量滴定的决定，并改善自我管理，最终改善与健康相关的生活质量。目的:我们的主要目的是评估基于网络的自我滴定程序对改善原发性高血压患者血压控制的效果。我们的第二个目标是评估该方案对改善与健康相关的生活质量的影响。方法:这是一项平行组、双盲、随机对照试验，在基线、3个月和6个月进行评估。研究对象为台湾北部某心脏病门诊部的原发性高血压患者(血压>130/80 mm Hg)，随机分为干预组和对照组。干预组接受基于网络的自我滴定程序，而对照组接受常规护理。随机分配对参与者和结果评估人员隐瞒。 Health-related quality of life was measured by the EuroQol five-dimension self-report questionnaire. We used generalized estimating equations to evaluate the effects of the intervention. Results: We included 222 patients and divided them equally into intervention (n=111) and control (n=111) groups. Patients receiving the Web-based self-titration program showed significantly greater improvement in the systolic and diastolic blood pressure control than those who did not receive this program, at 3 months (–21.4 mm Hg and –5.4 mm Hg, respectively; P<.001) and 6 months (–27.8 mm Hg and –9.7 mm Hg, respectively; P<.001). Compared with the control group, the intervention group showed a significant decrease in the overall defined daily dose at both 3 (–0.202, P=.003) and 6 (–0.236, P=.001) months. Finally, health-related quality of life improved significantly in the intervention group compared with the control group at both 3 and 6 months (both, P<.001). Conclusions: A Web-based self-titration program can provide immediate feedback to patients about how to control their blood pressure and manage their disease at home. This program not only decreases mean blood pressure but also increases health-related quality of life in patients with primary hypertension. Trial Registration: ClinicalTrials.gov NCT03470974; https://clinicaltrials.gov/ct2/show/NCT03470974 SN - 1438-8871 UR - //www.mybigtv.com/2019/12/e15836 UR - https://doi.org/10.2196/15836 UR - http://www.ncbi.nlm.nih.gov/pubmed/31804186 DO - 10.2196/15836 ID - info:doi/10.2196/15836 ER -