TY - JOUR AU - Zhang, Lei AU - He, Xingxing AU - Shen, Yun AU - Yu, Haoyong AU - Pan, jie - min AU - Zhu, Wei AU - Zhou, Jian AU - Bao, Yuqian PY - 2019 DA - 2019/12/9 TI -基于智能手机app的交互式管理对中国控制不良糖尿病患者血糖控制的有效性:随机对照试验JO - J Med Internet Res SP - e15401 VL - 21 IS - 12 KW - app KW -自我管理KW -互动管理KW -指导KW -糖化血红蛋白A1c KW -糖尿病AB -背景:近年来，移动医疗技术的快速发展为慢性疾病特别是糖尿病的长期管理提供了多种途径。智能手机应用作为一种新型的管理模式，具有全球化、便捷性、便捷性、便捷性、互动性等特点。虽然应用程序已被证明在血糖控制方面更有效，但与传统的计算机和基于网络的远程医疗技术相比，如何获得进一步和持续的改进仍在探索中。目的:本研究旨在探讨专业医疗团队基于app的互动管理模式对中国控制不良糖尿病患者血糖控制的有效性。方法:本研究是一项为期6个月的单中心前瞻性随机对照试验。共纳入276名1型或2型糖尿病患者，按1:1:1的比例随机分为对照组(A组)、应用程序自我管理组(B组)和应用程序交互管理组(C组)。主要结局是糖化血红蛋白(HbA1c)水平的变化。缺失数据采用多重imputation处理。结果:3组患者在第3、6个月时HbA1c水平均显著降低(均P<.05)。 Patients in the app interactive management group had a significantly lower HbA1clevel than those in the app self-management group at 6 months (P=.04). The average HbA1c reduction in the app interactive management group was larger than that in the app self-management and control groups at both months 3 and 6 (all P<.05). However, no differences in HbA1c reduction were observed between the app self-management and control groups at both months 3 and 6 (both P>.05). Multivariate line regression analyses also showed that the app interactive management group was associated with the larger reduction of HbA1c compared with groups A and B at both months 3 and 6 (all P>.05). In addition, the app interactive management group had better control of triglyceride and high-density lipoprotein cholesterol levels at both months 3 and 6 compared with baseline (both P<.05). Conclusions: In Chinese patients with poorly controlled diabetes, it was difficult to achieve long-term effective glucose improvement by using app self-management alone, but combining it with interactive management can help achieve rapid and sustained glycemic control. Trial Registration: ClinicalTrials.gov NCT02589730; https://clinicaltrials.gov/ct2/show/NCT02589730. SN - 1438-8871 UR - //www.mybigtv.com/2019/12/e15401 UR - https://doi.org/10.2196/15401 UR - http://www.ncbi.nlm.nih.gov/pubmed/31815677 DO - 10.2196/15401 ID - info:doi/10.2196/15401 ER -