TY - JOUR AU - Jacobi, Corinna AU - Hütter, Kristian AU - Völker, Ulrike AU - Möbius, Katharina AU - Richter, Robert AU - Trockel, Mickey AU - Jones Bell, Megan AU - Lock, James AU - Taylor, C Barr PY - 2018 DA - 2018/12/14 TI -基于父母的针对性预防神经性厌食症的有效性:随机对照试验JO - J Med Internet Res SP - e296 VL - 20 IS - 12kw -神经性厌食症KW -指症预防KW -网络KW -父母干预KW -随机对照试验AB -背景:网络预防干预可降低年轻高危女性暴食症和暴食障碍的风险和发生率。但对神经性厌食症(AN)核心症状的特异性作用较弱。目的:本研究的主要目的是评估一个指征的、基于父母的、基于网络的预防项目Eltern als Therapeuten (E@T)在减少an的危险因素和症状方面的效果。方法:选取11 - 17岁的女童进行AN的危险因素和早期症状筛查。然后，高危家庭被随机分配到E@T或仅作为评估对照条件。在干预前和干预后(6周后)以及6个月和12个月随访(FU)时进行评估。结果:在86所德国学校共发放了12,377份筛选问卷，包括同意的3941份。总体而言，477名(447/3941,12.10%)女孩被确定有患AN的风险，其中256名女孩可以联系到。总共66个家庭(66/256,25.8%的被联系的家庭)被随机分配到E@T或等待列表控制条件，43个(43/ 66,65%)参加了后评估，27个(27/ 66,41%)参加了12个月的FUs。 Due to low participation and high dropout rates of parents, recruitment was terminated prematurely. At 12-month FU, girls’ expected body weight (EBW) percentage was significantly greater for intervention participants compared with control participants (group by time interaction beta=21.0 [CI 5.81 to 36.13], P=.007; group by time squared interaction beta=−15.5 [CI −26.6 to −4.49], P=.007; estimated Cohen d=0.42]. No other significant effects were found on risk factors and attitudes of disturbed eating. Conclusions: Despite a significant increase in girls’ EBW percentage, parental participation and adherence to the intervention were low. Overall, parent-based, indicated prevention for children at risk for AN does not seem very promising, although it might be useful for parents who engage in the intervention. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 18614564; http://www.isrctn.com/ISRCTN18614564 (Archived by WebCite at http://www.webcitation.org/74FTV1EpF). SN - 1438-8871 UR - //www.mybigtv.com/2018/12/e296/ UR - https://doi.org/10.2196/jmir.9464 UR - http://www.ncbi.nlm.nih.gov/pubmed/30552078 DO - 10.2196/jmir.9464 ID - info:doi/10.2196/jmir.9464 ER -