TY - JOUR AU - Perry, Yael AU - Werner-Seidler, Aliza AU - Calear, Alison AU - Mackinnon, Andrew AU - King, Catherine AU - Scott, Jan AU - Merry, Sally AU - Fleming, Theresa AU - Stasiak, Karolina AU - Christensen, Helen AU - Batterham, Philip J PY - 2017 DA - 2017/11/02 TI -中学生预防抑郁症:基于学校的随机对照试验JO - J Med Internet Res SP - e369 VL - 19 IS - 11 KW -预防KW -抑郁KW -青少年KW -数字认知行为疗法AB -背景:抑郁症往往在青少年时期首次出现。越来越多的证据表明，普遍的抑郁症预防项目在学校环境中实施时，可能有能力减少抑郁症的影响。目的:本试验调查了SPARX-R的有效性，SPARX-R是一种游戏化在线认知行为治疗干预，用于预防抑郁症，相对于在面临重大压力源-中学期末考试之前向学生提供的注意力匹配控制干预。据推测，相对于对照组，在压力源之前进行预防干预会减少抑郁症状。方法:在澳大利亚悉尼的10所公立学校进行了一项聚类随机对照试验。参与者为540名最后一年级的中学生(平均16.7岁[SD 0.51]岁)，在学校水平的分组被随机分配到SPARX-R或对照干预。每周进行7个模块的干预，每个模块大约需要20到30分钟完成。主要结局是抑郁症症状(由重度抑郁症量表测量)。进行意向-治疗分析。 Results: Compared to controls, participants in the SPARX-R condition (n=242) showed significantly reduced depression symptoms relative to the control (n=298) at post-intervention (Cohen d=0.29) and 6 months post-baseline (d=0.21) but not at 18 months post-baseline (d=0.33). Conclusions: This is the first trial to demonstrate a preventive effect on depressive symptoms prior to a significant and universal stressor in adolescents. It demonstrates that an online intervention delivered in advance of a stressful experience can reduce the impact of such an event on the potential development or exacerbation of depression. Trial Registration: Australian New Zealand Clinical Trials Registry ACTRN12614000316606; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365986 (Archived by WebCite at http://www.webcitation.org/ 6u7ou1aI9) SN - 1438-8871 UR - //www.mybigtv.com/2017/11/e369/ UR - https://doi.org/10.2196/jmir.8241 UR - http://www.ncbi.nlm.nih.gov/pubmed/29097357 DO - 10.2196/jmir.8241 ID - info:doi/10.2196/jmir.8241 ER -