TY - JOUR AU - Milgrom, Jeannette AU - Danaher, Brian G AU - Gemmill, Alan W AU - Holt, Charlene AU - Holt, Christopher J AU - Seeley, John R AU - Tyler, Milagra S AU - Ross, Jessica AU - Ericksen, Jennifer PY - 2016 DA - 2016/03/07 TI -产后抑郁症女性的互联网认知行为治疗:MumMoodBooster JO - J Med Internet Res SP - e54 VL - 18 IS - 3kw -产后抑郁KW -产后抑郁KW -认知行为疗法KW -基于互联网的干预KW -随机对照试验AB -背景:很少有发表的研究基于互联网治疗产后抑郁症(PND)疗效的对照试验，也没有将诊断状态(临床缓解)评估为主要结果的对照试验。尽管需要改善治疗的接受和可及性，因为不到50%的产后抑郁症妇女寻求帮助，即使被确定为抑郁症。目的:在一项随机对照试验(RCT)中，我们旨在测试6期互联网干预(MumMoodBooster计划，先前在可行性试验中评估)对临床诊断为抑郁症的产后妇女样本的有效性。MumMoodBooster项目是一种认知行为疗法(CBT)干预，具有高度互动性，包括一个合作伙伴网站，并得到低强度电话指导的支持。方法:这是一个平行两组RCT (N=43)，比较网络CBT治疗(N= 21)和常规治疗(N= 22)。在基线和入组后12周，通过电话评估女性的诊断状况，采用DSM-IV (SCID-IV)标准临床访谈，采用贝克抑郁量表(BDI-II)评估症状严重程度。在整个研究期间，用患者健康问卷(PHQ-9)反复测量抑郁症状。结果:在研究结束时，接受网络CBT治疗的女性中，79%(15/19)不再符合SCID-IV抑郁症的诊断标准(2名干预参与者缺少这些结果数据)。相比之下，在常规治疗条件下，仅有18%(4/22)缓解。 Depression scores on the BDI-II showed a large effect favoring the intervention group (d=.83, 95% CI 0.20-1.45). Small to medium effects were found on the PHQ-9 and on measures of anxiety and stress. Adherence to the program was very good with 86% (18/21) of users completing all sessions; satisfaction with the program was rated 3.1 out of 4 on average. Conclusions: Our results suggest that our Internet CBT program, MumMoodBooster, is an effective treatment option for women clinically diagnosed with PND. This is one of only two controlled evaluations of specialized online psychological treatment among women clinically diagnosed with PND. MumMoodBooster appears to be a feasible, effective treatment option, which is potentially accessible to large numbers of women in metropolitan, rural, and remote areas. Future work might be focused profitably on establishing comparability with face-to-face treatments and purely self-guided delivery. We have commenced a larger RCT comparing MumMoodBooster with face-to-face CBT. Trial Registration: Australian and New Zealand Clinical Trials Registry (ANZCTR): ACTRN12613000113752; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363561 (Archived by WebCite® at http://www.webcitation.org/6f64kuyLf). SN - 1438-8871 UR - //www.mybigtv.com/2016/3/e54/ UR - https://doi.org/10.2196/jmir.4993 UR - http://www.ncbi.nlm.nih.gov/pubmed/26952645 DO - 10.2196/jmir.4993 ID - info:doi/10.2196/jmir.4993 ER -