TY - JOUR AU - Arean, Patricia A AU - Hallgren, Kevin A AU - Jordan, Joshua T AU - Gazzaley, Adam AU - Atkins, David C AU - Heagerty, Patrick J AU - Anguera, Joaquin A PY - 2016 DA - 2016/12/20 TI -抑郁症移动应用程序的使用和有效性:远程临床试验结果完全乔- J地中海互联网Res SP - e330六世- 18 - 12 KW -抑郁KW -移动应用KW -个随机对照试验KW -随机对照试验KW -认知训练KW - iPST KW -解决问题的治疗AB -背景:移动应用对心理健康有可能克服准入障碍精神卫生保健,但没有信息对病人是否使用干预措施为目的,他们对心理健康状况的影响。目的:我们研究的目的是记录和比较美国3种不同的抑郁症自助移动应用程序的使用模式和临床结果。研究人员通过网络广告和社交媒体招募参与者，并随机分配到3个情绪应用程序中的1个。治疗和评估在每个参与者的智能手机或平板电脑上远程进行，与研究人员的接触很少。我们招募了626名讲英语的成年人(≥18岁)，他们患有轻度至中度抑郁症，由9项患者健康问卷(PHQ-9)评分≥5或第10项评分≥2确定。这些应用分别是(1)Project: EVO，一款认知训练应用，理论上可以通过改善认知控制来缓解抑郁症状;(2)iPST，一款基于抑郁症循证心理治疗的应用;(3)Health Tips，一款治疗控制应用。结果为PHQ-9和Sheehan残疾量表得分。对治疗的坚持程度由参与者按照指示打开和使用应用程序的次数来衡量。结果:我们将211名参与者随机分配到iPST组，209人分配到EVO项目组，206人分配到健康提示组。 Among the participants, 77.0% (482/626) had a PHQ-9 score >10 (moderately depressed). Among the participants using the 2 active apps, 57.9% (243/420) did not download their assigned intervention app but did not differ demographically from those who did. Differential treatment effects were present in participants with baseline PHQ-9 score >10, with the cognitive training and problem-solving apps resulting in greater effects on mood than the information control app (χ22=6.46, P=.04). Conclusions: Mobile apps for depression appear to have their greatest impact on people with more moderate levels of depression. In particular, an app that is designed to engage cognitive correlates of depression had the strongest effect on depressed mood in this sample. This study suggests that mobile apps reach many people and are useful for more moderate levels of depression. ClinicalTrial: Clinicaltrials.gov NCT00540865; https://www.clinicaltrials.gov/ct2/show/NCT00540865 (Archived by WebCite at http://www.webcitation.org/6mj8IPqQr) SN - 1438-8871 UR - //www.mybigtv.com/2016/12/e330/ UR - https://doi.org/10.2196/jmir.6482 UR - http://www.ncbi.nlm.nih.gov/pubmed/27998876 DO - 10.2196/jmir.6482 ID - info:doi/10.2196/jmir.6482 ER -