TY -的盟Unlu因斯Burcin盟——Cuijpers Pim盟——范”t霍夫,伊迪丝非盟- van Ballegooijen Wouter AU -克里斯坦森,海伦盟——成熟,本意PY - 2013 DA - 2013/10/11 TI -基于互联网、文化敏感、问题解决与抑郁症治疗土耳其移民:随机对照试验乔- J地中海互联网Res SP - e227六世- 15 - 10 KW -抑郁KW -随机对照试验KW -民族KW -互联网KW -心理治疗AB -背景:居住在荷兰的土耳其移民有很高的抑郁症患病率，但在获得专业帮助方面遇到了相当大的障碍。提供便捷的互联网治疗可能有助于克服这些障碍。目的:本研究的目的是评估通过互联网进行的文化敏感、指导、自助、解决问题的干预对减少土耳其移民抑郁症状的有效性。方法:采用两组随机对照试验。主要结局指标为抑郁症状的严重程度;次要结局指标为躯体症状、焦虑、生活质量和治疗满意度。在基线、测试后(基线后6周)和基线后4个月对参与者进行在线评估。对意向治疗样本进行后测结果分析。采用多重imputation方法估计缺失值。 Differences in clinical outcome between groups were analyzed with a t test. Cohen’s d was used to determine the between-groups effect size at posttreatment and follow-up. Results: Turkish adults (N=96) with depressive symptoms were randomized to the experimental group (n=49) or to a waitlist control group (n=47). High attrition rates were found among the 96 participants of which 42% (40/96) did not complete the posttest (6 weeks) and 62% (59/96) participants did not complete the follow-up assessment at 4 months. No significant difference between the experimental group and the control group was found for depression at posttest. Recovery occurred significantly more often in the experimental group (33%, 16/49) than in the control group (9%, 4/47) at posttest (P=.02). Because of the high attrition rate, a completers-only analysis was conducted at follow-up. The experimental group showed significant improvement in depression compared to the control group both at posttest (P=.01) and follow-up (P=.01). Conclusions: The results of this study did not show a significant effect on the reduction of depressive symptoms. However, the effect size at posttest was high, which might be an indicator of the possible effectiveness of the intervention when assessed in a larger sample and robust trial. Future research should replicate our study with adequately powered samples. Trial Registration: Dutch Trial Register: NTR2303. http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2303 (Archived by WebCite at http://www.webcitation.org/6IOxNgoDu). SN - 14388871 UR - //www.mybigtv.com/2013/10/e227/ UR - https://doi.org/10.2196/jmir.2853 UR - http://www.ncbi.nlm.nih.gov/pubmed/24121307 DO - 10.2196/jmir.2853 ID - info:doi/10.2196/jmir.2853 ER -