TY -非盟的范德Zanden Rianne AU -克莱默,斜纹呢盟,gerrit Rob AU - Cuijpers Pim PY - 2012 DA - 2012/06/07 TI -在线团体课程的有效性在青少年和年轻成年人的抑郁症:一项随机试验乔- J地中海互联网Res SP - e86六世- 14 - 3 KW -电子健康,健康促进KW -抑郁症状KW -焦虑KW -青少年KW -互联网KW -随机对照试验AB -背景:抑郁症是一种严重的心理健康问题，通常在青春期首次发病。在线治疗可能为目前青少年抑郁症治疗不足的问题提供一个解决方案。对于有抑郁症状的成年人，基于互联网的认知行为疗法的有效性已经得到证实。这项研究是第一个调查在线抑郁治疗对有抑郁抱怨的年轻人有效性的随机对照试验之一，也是第一个关注在线小组课程的试验。目的:评估和讨论一个名为Grip op Je Dip(掌握你的情绪[MYM])的网络指导小组课程的有效性，该课程为16至25岁有抑郁症状的年轻人设计，与一个等待列表的对照组进行比较。方法:我们将244名有抑郁症状的年轻人随机分配到在线MYM课程或等待列表控制条件。主要结局指标为流行病学研究中心抑郁量表3个月后的治疗结果。次要结局是焦虑(用医院焦虑和抑郁量表衡量)和精通(精通量表)。我们研究了MYM组在基线后6个月的疗效维持情况。 Missing data were imputed. Results: The MYM group (n = 121) showed significantly greater improvement in depressive symptoms at 3 months than the control group (n = 123) (t187 = 6.62, P < .001), with a large between-group effect size of d = 0.94 (95% confidence interval [CI] 0.64–1.23). The MYM group also showed greater improvement in anxiety (t187 = 3.80, P < .001, d = 0.49, 95% CI 0.24–0.75) and mastery (t187 = 3.36, P = .001, d = 0.44, 95% CI 0.19–0.70). At 12 weeks, 56% (68/121) of the participants in the MYM group and 20% (24/123) in the control group showed reliable and clinically significant change. This between-group difference was significant (χ21 = 35.0, P < .001) and yielded a number needed to treat of 2.7. Improvements in the MYM group were maintained at 6 months. A limitation is the infeasibility of comparing the 6-month outcomes of the MYM and control groups, as the controls had access to MYM after 3 months. Conclusions: The online group course MYM was effective in reducing depressive symptoms and anxiety and in increasing mastery in young people. These effects persisted in the MYM group at 6 months. Trial Registration: Nederlands Trial Register: NTR1694; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1694 (Archived by WebCite at http://www.webcitation.org/683SBoeGV) SN - 1438-8871 UR - //www.mybigtv.com/2012/3/e86/ UR - https://doi.org/10.2196/jmir.2033 UR - http://www.ncbi.nlm.nih.gov/pubmed/22677437 DO - 10.2196/jmir.2033 ID - info:doi/10.2196/jmir.2033 ER -