TY - JOUR AU - Swan, Melanie PY - 2012 DA - 2012/03/07 TI -众包健康研究:一个重要的新兴补充临床试验在公共卫生研究生态系统中乔- J地中海互联网Res SP - e46六世- 14 - 2 KW -社区参与式研究KW -预防医学KW -个性化医疗KW -个性化医学KW -消费者参与KW -卫生服务研究KW -医疗保健研究KW——公共卫生KW -基因组KW -医学AB -背景:众包健康的关系是研究三当代趋势:1)公民科学(从事科学相关活动的非专业训练的个人);2)众包(利用基于网络的技术招募项目参与者);3)医疗2.0 /健康2.0(个人积极参与他们的医疗保健，特别是使用web 2.0技术)。众包健康研究是健康社会网络(在线健康兴趣社区)活动的自然延伸，可以由研究者组织，也可以由参与者组织。在过去几年中，专业研究人员一直在从健康社交网络中众包队列，以进行传统研究。参加者还开始通过专门为自我试验和调查与健康有关的问题而建立的保健社会网络和保健协作社区组织他们自己的研究。目的:本分析的目的是对众包健康研究进行全面的叙事审查。本综述将评估众包健康研究的现状、影响和前景。 Methods: Crowdsourced health research studies were identified through a search of literature published from 2000 to 2011 and informal interviews conducted 2008-2011. Keyword terms related to crowdsourcing were sought in Medline/PubMed. Papers that presented results from human health studies that included crowdsourced populations were selected for inclusion. Crowdsourced health research studies not published in the scientific literature were identified by attending industry conferences and events, interviewing attendees, and reviewing related websites. Results: Participatory health is a growing area with individuals using health social networks, crowdsourced studies, smartphone health applications, and personal health records to achieve positive outcomes for a variety of health conditions. PatientsLikeMe and 23andMe are the leading operators of researcher-organized, crowdsourced health research studies. These operators have published findings in the areas of disease research, drug response, user experience in crowdsourced studies, and genetic association. Quantified Self, Genomera, and DIYgenomics are communities of participant-organized health research studies where individuals conduct self-experimentation and group studies. Crowdsourced health research studies have a diversity of intended outcomes and levels of scientific rigor. Conclusions: Participatory health initiatives are becoming part of the public health ecosystem and their rapid growth is facilitated by Internet and social networking influences. Large-scale parameter-stratified cohorts have potential to facilitate a next-generation understanding of disease and drug response. Not only is the large size of crowdsourced cohorts an asset to medical discovery, too is the near-immediate speed at which medical findings might be tested and applied. Participatory health initiatives are expanding the scope of medicine from a traditional focus on disease cure to a personalized preventive approach. Crowdsourced health research studies are a promising complement and extension to traditional clinical trials as a model for the conduct of health research. SN - 1438-8871 UR - //www.mybigtv.com/2012/2/e46/ UR - https://doi.org/10.2196/jmir.1988 UR - http://www.ncbi.nlm.nih.gov/pubmed/22397809 DO - 10.2196/jmir.1988 ID - info:doi/10.2196/jmir.1988 ER -