TY -的盟Warmerdam Lisanne AU - van海峡,Annemieke盟——Twisk乔斯盟——成熟,本意非盟- Cuijpers Pim PY - 2008 DA - 2008/11/20 TI -网络治疗成人抑郁症状:随机对照试验乔- J地中海互联网Res SP e44六世- 10 - 4 KW -互联网KW -抑郁KW -自助KW -认知疗法KW -解决问题KW -随机试验AB -背景:许多抑郁症患者的症状得不到帮助，而且有各种各样的障碍阻碍他们寻求帮助。互联网可能为接触和帮助抑郁症患者提供有趣的选择。基于网络的认知行为疗法(CBT)可以有效治疗抑郁症，但基于问题解决疗法(PST)的短期干预可能是CBT的一个有价值的替代方案。目的:在本研究中，我们评估了基于网络的CBT和基于网络的PST与等待列表对照组(WL)的有效性，并确定了两种治疗方法之间的差异。方法:我们进行了一项三臂随机对照试验，比较CBT、PST和WL。主要的纳入标准是存在抑郁症状(在流行病学研究中心抑郁量表中≥16)。CBT和PST分别为每周8节课和5节课。参与者通过电子邮件获得支持。抑郁、焦虑和生活质量的自我报告测量在测试前和之后的5周、8周和12周完成。 Results: A total of 263 participants were randomized to the three conditions (CBT: n=88; PST: n=88; WL: n=87). Of the 263 participants, 184 (70%) completed questionnaires after 5 weeks, 173 (66%) after 8 weeks, and 151 (57%) after 12 weeks. Between-group effect sizes for depressive symptoms were 0.54 for CBT after 8 weeks (95% confidence interval (CI): 0.25 - 0.84) and 0.47 for PST after 5 weeks (95% CI: 0.17 - 0.77). These effects were further improved at 12 weeks (CBT: 0.69, 95% CI: 0.41 - 0.98; PST: 0.65, 95% CI: 0.36 - 0.95). For anxiety, effect sizes were also at a medium level. Effect sizes for quality of life were low. The number of participants showing clinically significant change at 12 weeks was significantly higher for CBT (n = 34, 38.6%) and PST (n = 30, 34.1%), compared to WL (n = 0). Conclusions: Both Internet-based treatments are effective in reducing depressive symptoms, although the effect of PST is realized more quickly. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 16823487; http://www.controlled-trials.com/ISRCTN16823487/16823487 (Archived by WebCite at http://www.webcitation.org/5cQsOj7xf). SN - 1438-8871 UR - //www.mybigtv.com/2008/4/e44/ UR - https://doi.org/10.2196/jmir.1094 UR - http://www.ncbi.nlm.nih.gov/pubmed/19033149 DO - 10.2196/jmir.1094 ID - info:doi/10.2196/jmir.1094 ER -