在网上招募的男男性行为者中，Crystal Methamphetamine的使用可预测性传播疾病的发生巢式病例对照研究%A Hirshfield,Sabina %A Remien,Robert H %A Walavalkar,Imelda %A Chiasson,Mary Ann %+纽约市医学与健康研究协会，Inc .， 40 Worth Street, Suite 720, New York NY 10013, USA， +1 212 285 0220 ext 115, shirshfield@mhra.org %K Internet %K性传播疾病%K甲基苯丙胺%K HIV %D 2004 %7 29.11.2004 %9原始论文%J J Med Internet Res %G English %X背景:在男男性行为者(MSM)中，自1999年以来新诊断的人类免疫缺陷病毒(HIV)感染人数增加了约60%。可能导致这种死灰复燃的因素包括广泛报道的艾滋病毒阳性和艾滋病毒阴性男男性行为者中细菌性传播疾病(性病)的增加，以及不安全的性行为。目的:本研究旨在进一步了解男男性接触者中与性病事件相关的危险行为。方法:采用巢式病例对照研究，收集2001年6个月期间MSM人群网络调查数据(N=2643)。使用卡方和逻辑回归方法来估计获得性病事件与没有性病的可能性。结果:85%的受访者是白人，46%的人年龄在30岁以下，80%的人在网上遇到性伴侣;7%为hiv阳性。有偶发性传播疾病的男性比没有性传播疾病的男性更有可能报告吸毒(冰毒比值比3.8;95%置信区间2.1 ~ 6.7; cocaine OR 2.3; 95% CI 1.2-4.2; ecstasy OR 2.2; 95% CI 1.3-3.8; Viagra OR 2.1; 95% CI 1.2-3.7), alcohol before or during sex (OR 1.9; 95% CI 1.2-2.9), and high-risk sexual behavior (unprotected anal intercourse OR 5.0; 95% CI 2.8-8.9; multiple sex partners OR 5.9; 95% CI 2.5-13.8). In the multivariate analysis, significant independent predictors associated with an incident STD were crystal methamphetamine use (adjusted OR 2.0; 95% CI 1.1-3.8), unprotected anal intercourse (adjusted OR 3.4; 95% CI 1.9-6.3), and 6 or more sex partners during the study period (adjusted OR 3.3; 95% CI 1.4-7.8). Conclusion: Identifying and treating MSM who have STDs, or who are at increased risk for acquiring STDs, is crucial in preventing the further spread of disease. In addition, there is a need to integrate HIV/STD and substance use prevention and education into Web-based and community-based venues. %M 15631965 %R 10.2196/jmir.6.4.e41 %U //www.mybigtv.com/2004/4/e41/ %U https://doi.org/10.2196/jmir.6.4.e41 %U http://www.ncbi.nlm.nih.gov/pubmed/15631965

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