使用商用可穿戴传感器数据和患者报告的结果表征流感样疾病负担:卡塔尔世界杯8强波胆分析混合方法队列研究%A Hunter,Victoria %A Shapiro,Allison %A Chawla,Devika %A Drawnel,Faye %A Ramirez,Ernesto %A Phillips,Elizabeth %A Tadesse-Bell,Sara %A Foschini,Luca %A Ukachukwu,Vincent %+ Roche Products Limited, 6 Falcon Way, Shire Park, Welwyn Garden City, al71tw，英国，44 7785642250，vincent.ukachukwu@roche.com %K流感%K流感样疾病%K可穿戴传感器%K个人产生的卫生保健数据%D 2023 %7 jj医学互联网研究%G英语%X背景:流感样疾病(ILI)的负担通常是通过住院和死亡来估计的。然而，不需要住院治疗的与il相关的发病率仍然缺乏特征。目的:本研究的主要目的是利用商用可穿戴传感器数据来表征ILI负担，并调查这些数据与自我报告的疾病严重程度和持续时间的相关性。此外，我们的目的是确定可穿戴传感器数据中与ILI相关的变化在求诊人群和非求诊人群以及确诊流感感染人群和仅出现ILI症状的人群之间是否存在差异。方法:本研究纳入FluStudy2020或呼吸道疾病家庭测试(HTRI)研究的参与者;这两项研究在设计上相似，并于2019年12月至2020年10月在美国进行。参与者通过每日、每两周和每月的调查自我报告ili相关症状和求医行为。FluStudy2020和HTRI分别记录了120天和150天的可穿戴传感器数据。 The following features were assessed: total daily steps, active time (time spent with >50 steps per minute), sleep duration, sleep efficiency, and resting heart rate. ILI-related changes in wearable sensor data were compared between the participants who sought health care and those who did not and between the participants who tested positive for influenza and those with symptoms only. Correlative analyses were performed between wearable sensor data and patient-reported outcomes. Results: After combining the FluStudy2020 and HTRI data sets, the final ILI population comprised 2435 participants. Compared with healthy days (baseline), the participants with ILI exhibited significantly reduced total daily steps, active time, and sleep efficiency as well as increased sleep duration and resting heart rate. Deviations from baseline typically began before symptom onset and were greater in the participants who sought health care than in those who did not and greater in the participants who tested positive for influenza than in those with symptoms only. During an ILI event, changes in wearable sensor data consistently varied with those in patient-reported outcomes. Conclusions: Our results underscore the potential of wearable sensors to discriminate not only between individuals with and without influenza infections but also between care-seeking and non–care-seeking populations, which may have future application in health care resource planning. Trial Registration: Clinicaltrials.gov NCT04245800; https://clinicaltrials.gov/ct2/show/NCT04245800 %M 36951890 %R 10.2196/41050 %U //www.mybigtv.com/2023/1/e41050 %U https://doi.org/10.2196/41050 %U http://www.ncbi.nlm.nih.gov/pubmed/36951890