在初级保健锚定的电子健康生活方式指导计划中的长期减肥:卡塔尔世界杯8强波胆分析随机对照试验%A Hesseldal,Laura %A Christensen,Jeanette Reffstrup %A Olesen,Thomas Bastholm %A Olsen,Michael Hecht %A Jakobsen,Pernille Ravn %A Laursen,Ditte Hjorth %A Lauridsen,Jørgen Trankjær %A Nielsen,Jesper Bo %A Søndergaard,Jens %A Brandt,Carl Joakim %+南丹麦大学公共卫生系全科医学研究单位，WP 9, J. B. Winsløws Vej 9A, 5000欧登塞，5000丹麦，45 314919945，lhesseldal@health.sdu.dk %K肥胖%K数字行为指导%K健康行为改变%K互动建议%K生活方式改变%K移动干预%K患者参与%K远程医疗%K电子健康%K数字健康%K数字教练%K减肥%K指导%K训练%K参与%K行为改变%K糖尿病%K 2型糖尿病%K T2D %D 2022 %7 23.9.2022 %9原始论文%J J J医学互联网研究%G英语%X肥胖患者长期减重可减少非传染性疾病的风险和进展。观察性研究表明，数字教练可以导致长期的体重减轻。目的:我们调查了与常规护理相比，eHealth生活方式指导项目是否对伴有或不伴有2型糖尿病的肥胖患者产生了显著的长期(12个月)体重减轻。方法:在丹麦50个城市进行的一项随机对照试验中，从2018年4月16日至2019年4月1日招募了340名伴有或不伴有2型糖尿病的肥胖患者，并通过自动计算机算法随机分为干预组(n=200)或对照组(n=140)。患者是通过全科医生、丹麦糖尿病组织和社交媒体招募的。数字指导干预包括最初的1小时面对面的动机访谈，然后是使用个人实时监控支持的行为改变技术的数字指导。主要结局是体重从基线到12个月的变化。 Results: Data were assessed for 200 participants, including 127 from the intervention group and 73 from the control group, who completed 12 months of follow-up. After 12 months, mean body weight and BMI were significantly reduced in both groups but significantly more so in the intervention group than the control group (–4.5 kg, 95% CI –5.6 to –3.4 vs –1.5 kg, 95% CI –2.7 to –0.2, respectively; P<.001; and –1.5 kg/m2, 95% CI –1.9 to –1.2 vs –0.5 kg/m2, 95% CI –0.9 to –0.1, respectively; P<.001). Hemoglobin A1c was significantly reduced in both the intervention (–6.0 mmol/mol, 95% CI –7.7 to –4.3) and control (–4.9 mmol/mol, 95% CI –7.4 to –2.4) groups, without a significant group difference (all P>.46). Conclusions: Compared to usual care, digital lifestyle coaching can induce significant weight loss for people living with obesity, both with and without type 2 diabetes, after 12 months. Trial Registration: ClinicalTrials.gov NCT03788915; https://clinicaltrials.gov/ct2/show/NCT03788915 %M 36149735 %R 10.2196/39741 %U //www.mybigtv.com/2022/9/e39741 %U https://doi.org/10.2196/39741 %U http://www.ncbi.nlm.nih.gov/pubmed/36149735

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