%0期刊文章%@ 1438- 8871% I JMIR出版物%V 23卡塔尔世界杯8强波胆分析% N 12% P e33877% T无安全套肛交与男男性行为者中HIV暴露前预防使用和性活动的异质分布相关:基于移动应用程序性日记数据的潜在类分析%A Yu, %A Wu, %A Ku,Stephane wenwei %A Huang, %A Li, %A chia wen, %A Poyao %A Strong,Carol %+国立成功大学医学院公共卫生系,台南大学路1号,70101,886 662353535,暴露前预防carol.chiajung@gmail.com % K移动应用% K % K预科% K潜类别分析% K与男性发生性关系的男性% K MSM % K避孕套% K性爱日记% K坚持% K程序% K性% K日记% K性健康% K HIV % K台湾% K风险预防% D % K原始论文7 23.12.2021 % 9 2021% % J J互联网Res % G英语% X背景:新的创新技术,如移动应用、开发增加暴露前预防(预科)依从性和使用日志性爱日记。移动应用程序的连续性减少了通常影响报告的避孕套和PrEP使用的回忆偏差。然而,目前使用的移动应用程序都不是为事件驱动的PrEP用户设计的,而且很少有研究证明了性日记数据的潜在用途,以促进了解性日记和PrEP使用的异质档案中不同的艾滋病毒风险。目的:我们的目的是区分不同类型的性事件和PrEP使用的异质档案,并检查不同类型的性事件中无安全套肛交的风险。方法:自2020年5月以来,我们从台湾的两个医疗中心招募了35名成年男性,随访4个月。参与者正在进行PrEP或愿意进行PrEP。他们被要求在移动应用程序上记录他们的性事件、PrEP使用情况和给药方案,以提高他们对PrEP的依从性。使用潜在分类分析来区分性事件和PrEP使用情况。指标包括每次性行为的正确PrEP摄入量、参与者的性姿势、伴侣的艾滋病毒状况和年龄。 Results: A total of 551 sex events were classified into three classes by latent class analysis: PrEP nonadherent flip-flopping (234/551, 42%), PrEP imperfect-adherent power bottoming (284/551, 52%), and PrEP adherent serodiscordant topping (33/551, 6%). “PrEP nonadherent flip-flopping” sex events were more likely to involve condomless anal sex than “PrEP imperfect-adherent power bottoming” (OR 1.83, 95% CI 1.03-3.25) after considering random intercepts for individuals, and this class needed to increase their PrEP adherence and use of condoms. “PrEP imperfect-adherent power bottoming” realized their own risk and packaged PrEP with condoms to protect themselves. Up to 99% (32/33) of sex events in “PrEP adherent serodiscordant topping” were protected by PrEP, but all of the sex events in this group were condomless. Conclusions: Using the sex diary data could advance the capacity to identify high-risk groups. HIV prevention strategy should be more flexible and combine PrEP with condom use for future HIV prevention. %M 34941560 %R 10.2196/33877 %U //www.mybigtv.com/2021/12/e33877 %U https://doi.org/10.2196/33877 %U http://www.ncbi.nlm.nih.gov/pubmed/34941560
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