自动编码器作为一种新的方法，在分析运动功能障碍患者的视频时保持数据隐私卡塔尔世界杯8强波胆分析:概念验证研究%A D’souza,Marcus %A Van Munster,Caspar E P %A Dorn,Jonas F %A Dorier,Alexis %A Kamm,Christian P %A Steinheimer,Saskia %A Dahlke,Frank %A Uitdehaag,Bernard M J %A Kappos,Ludwig %A Johnson,Matthew %+神经临床和门诊，巴塞尔大学医院和巴塞尔大学医学部，生物医学和临床研究部，瑞士巴塞尔，4031,41 61 265 4151，marcus.dsouza@usb.ch %K自动编码器%K视频评级%K机器学习算法%K深度神经网络%K神经状态- edss %D 2020 %7 8.5.2020 %9原始论文%J J医学互联网Res %G英文%X背景:在慢性神经疾病中，特别是多发性硬化(MS)，运动功能障碍的临床评估对监测患者的疾病至关重要。传统的量表不够灵敏，无法检测到细微的变化。患者表现的视频记录更准确，并增加了严重程度评级的可靠性。当这些记录自动化时，就可以通过机器学习算法创建定量残疾评估。这些算法的创建涉及非医疗保健专业人员，这对维护数据隐私是一个挑战。然而，自动编码器可以解决这个问题。目的:这项概念验证研究的目的是测试自动编码器的编码帧向量是否包含分析ms患者运动表现视频的相关信息。方法:在本研究中，记录了20个患者进行手指-鼻子测试的预评级视频。自动编码器从原始视频中创建编码帧向量，并再次解码视频。 The original and decoded videos were shown to 10 neurologists at an academic MS center in Basel, Switzerland. The neurologists tested whether the 200 videos were human-readable after decoding and rated the severity grade of each original and decoded video according to the Neurostatus-Expanded Disability Status Scale definitions of limb ataxia. Furthermore, the neurologists tested whether ratings were equivalent between the original and decoded videos. Results: In total, 172 of 200 (86.0%) videos were of sufficient quality to be ratable. The intrarater agreement between the original and decoded videos was 0.317 (Cohen weighted kappa). The average difference in the ratings between the original and decoded videos was 0.26, in which the original videos were rated as more severe. The interrater agreement between the original videos was 0.459 and that between the decoded videos was 0.302. The agreement was higher when no deficits or very severe deficits were present. Conclusions: The vast majority of videos (172/200, 86.0%) decoded by the autoencoder contained clinically relevant information and had fair intrarater agreement with the original videos. Autoencoders are a potential method for enabling the use of patient videos while preserving data privacy, especially when non–health-care professionals are involved. %M 32191621 %R 10.2196/16669 %U //www.mybigtv.com/2020/5/e16669 %U https://doi.org/10.2196/16669 %U http://www.ncbi.nlm.nih.gov/pubmed/32191621