%0期刊文章%@ 1438-8871 %I JMIR出版物%V 22%卡塔尔世界杯8强波胆分析 N 4% P e15863 %T单向短信对人乳头瘤病毒阳性坦桑尼亚妇女参加后续宫颈癌筛查的有效性(Connected2Care):平行组随机对照试验%A Linde,Ditte S %A Andersen,Marianne S %A Mwaiselage,Julius %A Manongi,Rachel %A Kjaer,Susanne K %A Rasch,Vibeke +南丹麦大学临床研究系,K øvervænget 10 Fl,欧登塞,5000,丹麦,45 61666564,dsondergaard@health.sdu.dk %K远程医疗%K宫颈癌%K HPV %K癌症早期发现%K非洲%D 2020 %7 2.4.2020 %9原始论文%J J医学互联网Res %G英文%X背景:快速人乳头瘤病毒(HPV) DNA检测在资源有限的国家是一种新兴的宫颈癌筛查策略,但它需要对HPV检测呈阳性的妇女进行随访。目的:本研究旨在确定单程短信是否能提高hpv阳性女性14个月随访宫颈癌筛查的出勤率。方法:这项多中心、平行组随机对照试验在坦桑尼亚的3家医院进行。符合条件的参与者年龄在25岁至60岁之间,在患者发起的快速HPV检测中检测呈阳性,已被告知其HPV结果,并拥有有效号码的私人手机。通过短信系统中的一种合并算法,参与者以1:1的比例随机分配到干预组或对照组。干预组收到单向短信,对照组没有收到短信。主要结果是参加了由卫生保健提供者发起的为期14个月的随访筛查。参与者没有盲法,但结果评估者是盲法。 The analysis was based on intention to treat. Results: Between August 2015 and July 2017, 4080 women were screened for cervical cancer, of which 705 were included in this trial—358 women were allocated to the intervention group, and 347 women were allocated to the control group. Moreover, 16 women were excluded before the analysis because they developed cervical cancer or died (8 from each group). In the intervention group, 24.0% (84/350) women attended their follow-up screening, and in the control group, 23.8% (80/335) women attended their follow-up screening (risk ratio 1.02, 95% CI 0.79-1.33). Conclusions: Attendance to a health provider-initiated follow-up cervical cancer screening among HPV-positive women was strikingly low, and one-way text messages did not improve the attendance rate. Implementation of rapid HPV testing as a primary screening method at the clinic level entails the challenge of ensuring a proper follow-up of women. Trial Registration: ClinicalTrials.gov NCT02509702; https://clinicaltrials.gov/ct2/show/NCT02509702. International Registered Report Identifier (IRRID): RR2-10.2196/10.2196/15863 %M 32238335 %R 10.2196/15863 %U //www.mybigtv.com/2020/4/e15863/ %U https://doi.org/10.2196/15863 %U http://www.ncbi.nlm.nih.gov/pubmed/32238335
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