医师引导的基于网络的认知行为治疗压力相关障碍的成本-效果研究卡塔尔世界杯8强波胆分析随机对照试验的二次分析% a Lindsäter,Elin % a Axelsson,Erland % a Salomonsson,Sigrid % a Santoft,Fredrik % a Ljótsson,Brjánn % a Åkerstedt,Torbjörn % a Lekander,Mats % a Hedman-Lagerlöf,Erik %+诺贝尔奖väg 9,17165斯德哥尔摩索尔纳，瑞典，46 735635233，elin.lindsater@ki.se %K心理压力%K适应障碍%K衰竭障碍%K认知行为治疗%K成本效益%K互联网%D 2019 %7 13.09.2019 %9背景:压力相关障碍与显著的痛苦、功能损害和高社会成本相关。基于网络的认知行为疗法(ICBT)是一种很有前景的治疗压力相关疾病的方法，但迄今为止尚未进行健康经济评估。目的:本研究的目的是评估ICBT治疗以适应障碍(AD)或衰竭障碍(ED)形式出现的压力相关障碍患者的成本-效果和成本-效用。我们假设ICBT与等候名单对照组(WLC)相比，将以较低的净成本产生改善，从而使其具有成本效益。方法:健康经济数据与一项为期12周的ICBT随机对照试验相结合，其中100例患者被随机分为ICBT组(N= 50)和WLC组(N= 50)。对治疗前后的健康结果和成本进行了调查。我们计算了基于缓解率的增量成本-效果比(ICERs)和基于健康相关生活质量的增量成本-效用比(ICURs)。采用自举抽样来评估结果的不确定性。 Results: The ICER indicated that the most likely scenario was that ICBT led to higher remission rates compared with the WLC and was associated with slightly larger reductions in costs from pre- to posttreatment. ICBT had a 60% probability of being cost-effective at a willingness to pay (WTP) of US $0 and a 96% probability of being cost-effective at a WTP of US $1000. The ICUR indicated that ICBT also led to improvements in quality of life at no net societal cost. Sensitivity analyses supported the robustness of our results. Conclusions: The results suggest that ICBT is a cost-effective treatment for patients suffering from AD or ED. Compared with no treatment, ICBT for these patients yields large effects at no or minimal societal net costs. Trial Registration: ClinicalTrials.gov NCT02540317; https://clinicaltrials.gov/ct2/show/NCT02540317 %M 31586370 %R 10.2196/14675 %U //www.mybigtv.com/2019/9/e14675 %U https://doi.org/10.2196/14675 %U http://www.ncbi.nlm.nih.gov/pubmed/31586370