%0期刊文章%@ 1438- 8871% I JMIR出版物%V 21卡塔尔世界杯8强波胆分析% N 6% P e1256 %T引导自助作品:Pacifica的随机候补对照试验，一个移动应用程序集成认知行为疗法和正念压力，焦虑和抑郁% a Moberg,Christine % a Niles,Andrea % a Beermann,Dale + Pacifica实验室，Inc, 150 S第五街，套房825，明尼阿波利斯，明尼苏达州，55402，美国，1 6083470325，christine.moberg@gmail.com %K mHealth %K焦虑%K抑郁%K压力%K认知行为治疗%K智能手机应用程序%D 2019 %7 8.6.2019 %9原始论文%J J医学互联网Res %G英文%X背景:尽管技术有了长足的进步，消费者对技术支持的行为健康工具的需求也在增加，但在减轻精神疾病负担方面却进展甚微。这可能是因为在快速发展的技术环境中进行传统临床试验的固有挑战。目的:本研究旨在验证Pacifica的有效性，Pacifica是一款流行的商用应用程序，用于轻度至中度压力、焦虑和抑郁的自我管理。方法:从应用程序内入职招募了500名患有轻度至中度焦虑或抑郁的成年人，参与Pacifica的随机等待列表对照试验。我们进行了一项全虚拟研究，通过基于web的参与者门户网站招募、筛选和随机选择参与者。研究参与者使用该应用程序1个月，不要求使用级别，密切模仿现实世界应用程序的使用情况。等待列表组的参与者在1个月后可以使用该应用程序。测量方法包括自我报告的压力、焦虑、抑郁和自我效能症状。 We performed an intent-to-treat analysis to examine the interactive effects of time and condition. Results: We found significant interactions between time and group. Participants in the active condition demonstrated significantly greater decreases in depression, anxiety, and stress and increases in self-efficacy. Although we did not find a relationship between overall engagement with the app and symptom improvement, participants who completed relatively more thought record exercises sustained improvements in their symptoms through the 2-month follow-up to a greater degree than those who completed fewer. In addition, we found that participants who reported concomitantly taking psychiatric medications during the trial benefitted less from the app, as measured by the symptoms of anxiety and stress. Conclusions: This study provides evidence that Pacifica, a popular commercially available self-help app, is effective in reducing self-reported symptoms of depression, anxiety, and stress, particularly among individuals who utilize thought records and are not taking psychiatric medication. Trial Registration: ClinicalTrials.gov NCT03333707; https://clinicaltrials.gov/ct2/show/NCT03333707 (Archived by WebCite at http://www.webcitation.org/78YE07ADB) %M 31199319 %R 10.2196/12556 %U //www.mybigtv.com/2019/6/e12556/ %U https://doi.org/10.2196/12556 %U http://www.ncbi.nlm.nih.gov/pubmed/31199319