在早期药物开发临床中，癌症相关的互联网使用及其与患者决策和对医生的信任卡塔尔世界杯8强波胆分析的关系:横断面观察研究,摄取%乔治,金黄的C % Iwuanyanwu, Eucharia C %布福德,阿德莉娅娜S % Piha-Paul, Sarina %印度,Vivek %富,中国科学院%卡普,丹尼尔·D %裤子Shubham % Hinojosa,克里斯蒂娜·O %赫斯克力夫兰肯尼斯·R %,查尔斯·S % Bernstam Elmer V % Meric-Bernstam,基础%香港,大卫·S % +临床实验的癌症疗法、德克萨斯大学MD安德森癌症中心,休斯顿,TX,美国,1 7137941347,ggeorge2@mdanderson.org %K癌症%K临床试验%K医生%K早期临床试验%K互联网%K患者%K医生%K医患关系%K症状%D 2019 %7 14.03.2019 %9原始论文%J J医学互联网Res %G英文%X背景:在早期临床试验临床中与癌症相关的互联网用户(CIUs)患者中，癌症相关互联网使用对医患关系的作用尚未得到充分的探索。目的:我们研究了癌症相关互联网使用与早期药物开发临床中CIUs的医患关系和决策之间的关系。方法:291例完成网络使用问卷的I期临床患者中，179例为ciu。根据患者出生年份来定义世代:“千禧一代”(1990年以后)和“X/Y一代”(1965-1990年)被分组为“千禧一代或X/Y一代”;《婴儿潮一代》(1946-1964);以及《伟大或沉默的一代》(1945年及更早)。统计分析包括Wilcoxon配对符号秩检验和Mann-Whitney U检验。结果:CIUs中52%(94/179)为女性，44%(78/179)年龄大于60岁，60%(108/179)家庭收入超过6万美元。 The sources of information on cancer and clinical trials included physicians (171/179, 96%), the internet (159/179, 89%), and other clinical trial personnel (121/179, 68%). For the overall sample and each generation, the median values for trust in referring and Phase I clinical trial physicians among early drug development clinic CIUs were 5 on a 0-5 scale, with 5 indicating “complete trust.” CIUs’ trust in their referring (5) and phase 1 (5) physicians was higher than CIUs’ trust in Web-based cancer-related information (3; P<.001 for both). CIUs who reported visiting the National Cancer Institute (NCI) website, NCI.org, to learn about cancer reported higher levels of trust in Web-based cancer-related information than CIUs who did not use the NCI website (P=.02). Approximately half of CIUs discussed internet information with their doctor. Only 14% (23/165) of CIUs had asked their physician to recommend cancer-related websites, and 24% (35/144) of CIUs reported at least occasional conflict between their physician’s advice and Web-based information. Conclusions: Despite the plethora of websites related to cancer and cancer clinical trials, patients in early-phase clinical trial settings trust their physicians more than Web-based information. Cancer-related organizations should provide regularly updated links to trustworthy websites with cancer and clinical trial information for patients and providers and educate providers on reliable cancer websites so that they can better direct their patients to appropriate internet content. %M 30869638 %R 10.2196/10348 %U //www.mybigtv.com/2019/3/e10348/ %U https://doi.org/10.2196/10348 %U http://www.ncbi.nlm.nih.gov/pubmed/30869638