%0期刊文章%@ 1438-8871 %I JMIR出版物%V 21%卡塔尔世界杯8强波胆分析 N 10% P e15455% T公众关注监控推特用户及其对话以招募临床试验:调查研究%A Reuter,Katja %A Zhu,Yifan %A Angyan,Praveen %A Le,NamQuyen %A Merchant,Akil A Zimmer,Michael %+南加州大学凯克医学院，南加州临床和转化科学研究所，洛杉矶Alcazar街2250号，CA 90089，美国，1 3234422046，katja.reuter@gmail.com %K艾滋病%K癌症%K临床研究%K临床试验%K众包%K伦理%K HIV %K HPV %K知情同意%K互联网%K研究伦理%K机械土耳其%K MTurk %K监测%K肥胖%K隐私%K舆论%K招聘%K吸烟%K社交媒体%K社交网络%K监测%K TurkPrime %K推特%D 2019 %7 30.10.2019 %9原创论文%J J医学互联网Res %G英语%X背景:Twitter等社交网络为临床研究界提供了一个基于用户活动数据吸引潜在研究参与者的新机会。然而，公共社交媒体数据的可用性导致了新的伦理挑战，涉及尊重用户隐私和监测临床试验招募社交媒体的适当性。研究人员表示，有必要在道德规范和规章的制定中纳入用户的观点。目的:本研究调查了Twitter用户和非Twitter用户对使用Twitter监控社交媒体用户及其对话以招募潜在临床试验参与者的态度和关注程度。方法:我们使用两种在线方法招募研究参与者:开放调查(1)于2017年5月23日至6月8日在Twitter上发布，(2)于2017年5月23日至6月8日在众包数据采集平台TurkPrime上部署。符合条件的参与者是成年人，18岁或以上，谁居住在美国。有推特账户和没有推特账户的人都参与了这项研究。 Results: While nearly half the respondents—on Twitter (94/603, 15.6%) and on TurkPrime (509/603, 84.4%)—indicated agreement that social media monitoring constitutes a form of eavesdropping that invades their privacy, over one-third disagreed and nearly 1 in 5 had no opinion. A chi-square test revealed a positive relationship between respondents’ general privacy concern and their average concern about Internet research (P<.005). We found associations between respondents’ Twitter literacy and their concerns about the ability for researchers to monitor their Twitter activity for clinical trial recruitment (P=.001) and whether they consider Twitter monitoring for clinical trial recruitment as eavesdropping (P<.001) and an invasion of privacy (P=.003). As Twitter literacy increased, so did people’s concerns about researchers monitoring Twitter activity. Our data support the previously suggested use of the nonexceptionalist methodology for assessing social media in research, insofar as social media-based recruitment does not need to be considered exceptional and, for most, it is considered preferable to traditional in-person interventions at physical clinics. The expressed attitudes were highly contextual, depending on factors such as the type of disease or health topic (eg, HIV/AIDS vs obesity vs smoking), the entity or person monitoring users on Twitter, and the monitored information. Conclusions: The data and findings from this study contribute to the critical dialogue with the public about the use of social media in clinical research. The findings suggest that most users do not think that monitoring Twitter for clinical trial recruitment constitutes inappropriate surveillance or a violation of privacy. However, researchers should remain mindful that some participants might find social media monitoring problematic when connected with certain conditions or health topics. Further research should isolate factors that influence the level of concern among social media users across platforms and populations and inform the development of more clear and consistent guidelines. %R 10.2196/15455 %U //www.mybigtv.com/2019/10/e15455/ %U https://doi.org/10.2196/15455