期刊文章%@ 1438-8871 %I JMIR出版物%V 19 %N卡塔尔世界杯8强波胆分析 11 %P e369 %T预防高三中学生抑郁:基于学校的随机对照试验%A Perry,Yael %A Werner-Seidler,Aliza %A Calear,Alison %A Mackinnon,Andrew %A King,Catherine %A Scott,Jan %A Merry,Sally %A Fleming,Theresa %A Stasiak,Karolina %A Christensen,Helen %A Batterham,Philip J %+黑狗研究所，新南威尔士大学，兰德威克医院路，61 2 9382 8208，h.christensen@blackdog.org.au %K预防%K抑郁症%K青少年%K数字认知行为疗法%D 2017 %7 02.11.2017 %9原创论文%J J医学互联网Res %G英语%X背景:抑郁症往往在青少年时期首次出现。越来越多的证据表明，如果在学校环境中实施，普遍的抑郁症预防项目可能有能力减少抑郁症的影响。目的:本试验调查了SPARX-R的有效性。SPARX-R是一种游戏化的在线认知行为治疗干预，用于预防抑郁症，相对于在学生面临重大压力源——中学期末考试之前提供的注意匹配控制干预。假设在压力源之前提供预防干预会减少相对于对照组的抑郁症状。方法:在澳大利亚悉尼的10所公立学校进行了一项聚类随机对照试验。参与者为540名大四中学生(平均16.7岁[SD 0.51]岁)，在学校层面随机分配到SPARX-R或对照干预组。每周提供7个模块的干预措施，每个模块大约需要20到30分钟完成。主要结局是抑郁症症状，通过重度抑郁症量表进行测量。 Intention-to-treat analyses were performed. Results: Compared to controls, participants in the SPARX-R condition (n=242) showed significantly reduced depression symptoms relative to the control (n=298) at post-intervention (Cohen d=0.29) and 6 months post-baseline (d=0.21) but not at 18 months post-baseline (d=0.33). Conclusions: This is the first trial to demonstrate a preventive effect on depressive symptoms prior to a significant and universal stressor in adolescents. It demonstrates that an online intervention delivered in advance of a stressful experience can reduce the impact of such an event on the potential development or exacerbation of depression. Trial Registration: Australian New Zealand Clinical Trials Registry ACTRN12614000316606; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365986 (Archived by WebCite at http://www.webcitation.org/ 6u7ou1aI9) %M 29097357 %R 10.2196/jmir.8241 %U //www.mybigtv.com/2017/11/e369/ %U https://doi.org/10.2196/jmir.8241 %U http://www.ncbi.nlm.nih.gov/pubmed/29097357

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