%0杂志文章%@ 1438-8871 %I JMIR出版物%V 18%卡塔尔世界杯8强波胆分析 N 12% P e330% T抑郁症手机应用程序的使用和有效性:来自一个完全远程临床试验的结果，Patricia a . Hallgren,Kevin a . Jordan,Joshua T . a . Gazzaley,Adam a . Atkins,David C . a . Heagerty,Patrick J . a Anguera,Joaquin a . +加州大学旧金山分校神经学系，675 Nelson Rising Lane，旧金山，CA, 94158，美国，1415 502 7322，joaquin.anguera@ucsf.edu %K抑郁症%K移动应用程序%K随机对照试验%K认知训练%K iPST %K问题解决疗法%D 2016 %7 20.12.2016 %9原始论文%J J医学互联网Res %G英语%X背景:用于心理健康的移动应用程序有可能克服心理健康保健的访问障碍，但关于患者是否按预期使用干预措施以及它们对心理健康结果的影响，几乎没有信息。目的:我们研究的目的是记录和比较美国3种不同的抑郁症自助移动应用程序的使用模式和临床结果。研究人员通过网络广告和社交媒体招募参与者，并随机分配到3个情绪应用程序中的1个。治疗和评估在每个参与者的智能手机或平板电脑上远程进行，与研究人员的接触很少。我们招募了626名讲英语的成年人(≥18岁)，他们患有轻度至中度抑郁症，由9项患者健康问卷(PHQ-9)评分≥5或第10项评分≥2确定。这些应用分别是(1)Project: EVO，一款认知训练应用，理论上可以通过改善认知控制来缓解抑郁症状;(2)iPST，一款基于抑郁症循证心理治疗的应用;(3)Health Tips，一款治疗控制应用。结果为PHQ-9和Sheehan残疾量表得分。对治疗的坚持程度由参与者按照指示打开和使用应用程序的次数来衡量。 Results: We randomly assigned 211 participants to iPST, 209 to Project: EVO, and 206 to Health Tips. Among the participants, 77.0% (482/626) had a PHQ-9 score >10 (moderately depressed). Among the participants using the 2 active apps, 57.9% (243/420) did not download their assigned intervention app but did not differ demographically from those who did. Differential treatment effects were present in participants with baseline PHQ-9 score >10, with the cognitive training and problem-solving apps resulting in greater effects on mood than the information control app (χ22=6.46, P=.04). Conclusions: Mobile apps for depression appear to have their greatest impact on people with more moderate levels of depression. In particular, an app that is designed to engage cognitive correlates of depression had the strongest effect on depressed mood in this sample. This study suggests that mobile apps reach many people and are useful for more moderate levels of depression. ClinicalTrial: Clinicaltrials.gov NCT00540865; https://www.clinicaltrials.gov/ct2/show/NCT00540865 (Archived by WebCite at http://www.webcitation.org/6mj8IPqQr) %M 27998876 %R 10.2196/jmir.6482 %U //www.mybigtv.com/2016/12/e330/ %U https://doi.org/10.2196/jmir.6482 %U http://www.ncbi.nlm.nih.gov/pubmed/27998876