%0期刊文章@ 1438- 8871% I JMIR出版公司V 17%卡塔尔世界杯8强波胆分析 N 6% P 144% T在社交媒体上接触和表达对人乳头瘤病毒疫苗的负面意见之间的关联:一项观察性研究%A Dunn,Adam G %A Leask,Julie %A Zhou，徐娟%A Mandl,Kenneth D %A Coiera,Enrico %+健康信息中心，澳大利亚麦考瑞大学，L6 75 Talavera Rd，悉尼，2109，澳大利亚，61 298502413,adam.dunn@mq.edu.au %K HPV疫苗%K推特消息%K社交媒体%K公共卫生监测%K社交网络%D 2015 %7 10.06.2015 %9原始论文%J J Med Internet Res %G英文%X背景:一些团体和个人在网络和社交媒体上非常活跃，试图对疫苗接种的安全性和价值的公众舆论产生负面影响，并可能影响一些社区的决策。目的:我们试图通过明确测量Twitter社区社会结构中潜在的信息暴露，来衡量在Twitter社区中接触到关于人类乳头瘤病毒(HPV)疫苗的负面意见是否与随后的负面意见表达相关。方法:我们假设，先前接触拒绝HPV疫苗安全性或价值的意见与发布类似意见的风险增加有关，并通过分析Twitter上发布的消息的时间序列来验证这一假设。研究设计是对与HPV疫苗相关的推文和用户之间的社会联系进行回顾性分析。在2013年10月至2014年4月期间，我们收集了83551条英语推文，其中包括与HPV疫苗相关的术语，以及30621名发布或转发推文的用户中的957865个社交关系。使用之前在手动标记样本上训练过的机器学习分类器，将推文分类为表达负面或中性/积极观点。结果:在6个月的时间里，25.13%(20,994/83,551)的推文被归类为负面;在30621名发布HPV疫苗推文的用户中，9046人(29.54%)接触了大多数负面推文。 The likelihood of a user posting a negative tweet after exposure to a majority of negative opinions was 37.78% (2780/7361) compared to 10.92% (1234/11,296) for users who were exposed to a majority of positive and neutral tweets corresponding to a relative risk of 3.46 (95% CI 3.25-3.67, P<.001). Conclusions: The heterogeneous community structure on Twitter appears to skew the information to which users are exposed in relation to HPV vaccines. We found that among users that tweeted about HPV vaccines, those who were more often exposed to negative opinions were more likely to subsequently post negative opinions. Although this research may be useful for identifying individuals and groups currently at risk of disproportionate exposure to misinformation about HPV vaccines, there is a clear need for studies capable of determining the factors that affect the formation and adoption of beliefs about public health interventions. %M 26063290 %R 10.2196/jmir.4343 %U //www.mybigtv.com/2015/6/e144/ %U https://doi.org/10.2196/jmir.4343 %U http://www.ncbi.nlm.nih.gov/pubmed/26063290