%0期刊文章@ 14388871 %I JMIR出版公司%V 15%卡塔尔世界杯8强波胆分析 N 12% P e276% T Sexunzipped Trial:年轻人对参与在线随机对照试验的看法尼古拉斯，安吉拉，贝利，茱莉亚，史蒂文森，菲奥娜，默里，伊丽莎白，初级保健和人口健康研究部，伦敦大学学院，皇家自由医院三楼，伦敦，NW3 2PF, 44 2077940500 ext 36747，julia.bailey@ucl.ac.uk %K互联网%K随机对照试验%K定性研究%K结局评估(卫生保健)%K性健康%K沙眼衣原体%D 2013 %7 12.12.2013 %9原始论文%J J医学互联网Res %G英文%X背景:英国年轻人中性传播感染(STIs)的发病率正在上升。由于互联网在年轻人中使用率很高，有可能产生匿名感，而且易于获取，因此可以成为提供性健康信息和促进性健康的适当媒介。在线随机对照试验(rct)越来越多地用于评估在线干预措施，但尽管在线方法有许多优点，但它们也可能与许多问题有关，包括在线干预措施的参与度低、试验保留率低以及对在线自我报告收集的数据有效性的担忧。我们进行了一项在线可行性试验，测试了sexunzip网站对性健康的影响，并将其与纯信息网站进行了比较。本研究报告对试验程序进行了定性评估，描述了参与者对Sexunzipped在线试验的经验和观点，包括招募方法、激励措施、联系方法和性健康结果测量。目的:我们的目标是确定参与者对sexunzip干预试验RCT中使用的在线试验方法的可接受性和有效性的看法。方法:我们使用三个定性数据来源来评估在线试点RCT方法的可接受性和有效性:(1)与来自试点RCT的22名参与者的单独访谈，(2)试验协调员从试验参与者那里收到的133封电子邮件，以及(3)来自基线和随访问卷的217条自由文本评论。采访进行了录音和逐字抄录。 An iterative, thematic analysis of all three data sources was conducted to identify common themes related to the acceptability and feasibility of the online trial methodology. Results: Interview participants found the trial design, including online recruitment via Facebook, online registration, email communication with the researchers, and online completion of sexual health questionnaires to be highly acceptable and preferable to traditional methods. Incentives might assist in recruiting those who would not otherwise participate. Participants generally enjoyed taking part in sexual health research online and found the questionnaire itself thought-provoking. Completing the sexual health questionnaires online encouraged honesty in responding that might not be achieved with other methods. The majority of interview participants also thought that receiving and returning a urine sample for chlamydia testing via post was acceptable. Conclusions: These findings provide strong support for the use of online research methods for sexual health research, emphasizing the importance of careful planning and execution of all trial procedures including recruitment, respondent validation, trial related communication, and methods to maximize follow-up. Our findings suggest that sexual health outcome measurement might encourage reflection on current behavior, sometimes leading to behavior change. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 55651027; http://www.controlled-trials.com/isrctn/pf/55651027 (Archived by WebCite at http://www.webcitation.org/6LbkxdPKf). %M 24334198 %R 10.2196/jmir.2647 %U //www.mybigtv.com/2013/12/e276/ %U https://doi.org/10.2196/jmir.2647 %U http://www.ncbi.nlm.nih.gov/pubmed/24334198