基于网络的认知行为自助干预减少问题可卡因使用者的可卡因消费量随机对照试验%A Schaub,Michael %A Sullivan,Robin %A Haug,Severin %A Stark,Lars %+苏黎世大学附属公共卫生与成瘾研究所，瑞士苏黎世，康拉德街32号，41 44 448 11 65,michael.schaub@isgf.uzh.ch %K可卡因%K认知行为疗法%K互联网%K随机对照试验%D 2012 %7 28.11.2012 %9原始论文%J J Med Internet Res %G English %X减少问题药物使用的网络自助项目能够触及普通人群中隐藏的消费群体。这些方案的特点是其低治疗门槛和非限制性干预设置。它们还具有成本效益，使保健费用不断增加的低收入和高收入工业化国家都感兴趣。目的:测试匿名、全自动、基于网络的自助干预作为可卡因使用者门诊治疗服务的替代方案的可行性和有效性。方法:通过各种线上和线下媒体招募共计196名可卡因吸食者，进行随机对照试验。干预组的参与者接受互动认知行为模块和消费日记，以减少可卡因的使用，而对照组的参与者接受在线心理教育信息模块。在4周、6周和6个月后进行基于网络的随访评估。观察干预组和对照组的治疗保留情况并进行比较。 Severity of cocaine dependence was the main outcome measure. Secondary outcomes were cocaine craving, depression symptoms, and alcohol and other substance use. Results: This Web-based intervention attracted older and more educated participants than existing outpatient treatment programs for which cocaine is the primary substance of abuse. Participants in the intervention group showed greater treatment retention compared with the control group (P = .04). Low response rates at the follow-up assessments restricted the explanatory power of the analyses. At the follow-up assessments, the severity of cocaine dependence did not differ between the intervention and control groups (P = .75). Furthermore, there were no differences in cocaine craving, depression, or alcohol and other substance use. Using the consumption diaries, the average number of cocaine-free days per week did not change significantly, whereas the weekly quantity of cocaine used decreased equally in both groups (P = .009). Conclusions: For cocaine users with low dependence severity, a fully automated Web-based cognitive behavioral self-help intervention is a feasible alternative with limited effectiveness in outpatient treatment services. However, this type of intervention may attract specific user groups that are rarely reached by existing outpatient treatment and may help them to control their cocaine consumption anonymously. Trial Registration: ISRCTN93702927; http://www.controlled-trials.com/ISRCTN93702927 (Archived by WebCite at http://www.webcitation.org/6CTMM10MR) %M 23192752 %R 10.2196/jmir.2244 %U //www.mybigtv.com/2012/6/e166/ %U https://doi.org/10.2196/jmir.2244 %U http://www.ncbi.nlm.nih.gov/pubmed/23192752