杂志文章@ 1448 -8871 %I Gunther Eysenbach V 14% N 2% P e57% T一个针对超重和肥胖成年人的12周商业网络减肥计划:比较基本特征和增强特征的随机对照试验A Collins,Clare E %A Morgan,Philip J %A Jones,Penelope A Fletcher,Kate A Martin,Julia A Aguiar,Elroy J %A Lucas,Ashlee A Neve,Melinda J %A Callister,Robin +营养和饮食学，纽卡斯尔大学健康科学学院，健康学院，HA 12 Hunter Building, University Drive, Callaghan, NSW, 2308，澳大利亚，61 2 49215646，clare.collins@newcastle.edu.au %K干预%K减肥%K网络干预%K随机对照试验%K减肥饮食%K eHealth %D 2012 %7 25.04.2012 %9原始论文%J J医学互联网Res %G英文%X背景:基于网络的减肥计划的开发和使用正在迅速增加，但很少使用随机对照试验(rct)对其进行评估。有趣的是，大多数尝试减肥的人都使用商业上可获得的项目，但商业项目很少被独立或严格地评估。目的:比较标准的基于网络的商业减肥计划(基本)与该网络计划的增强版(增强版)在超重和肥胖成人的体重结果方面提供额外的个性化电子反馈和提供者联系(对照组)。方法:这项纯基于网络的试验使用了一个封闭的在线用户组，是一种评估者盲法随机对照试验，参与者随机分配到基于社会认知理论的基础或增强的12周基于网络的项目，或以体重指数(BMI)为主要结果的对照组。结果:我们招募了309名成人(129/309,41.8%男性，BMI平均值32.3,SD 4 kg/m2)， 84.1%(260/309)在12周内留存。意向治疗分析显示，与对照组相比，两个干预组的BMI均有所降低(基本组:-0.72,SD 1.1 kg/m2，增强组:-1.0,SD 1.4，对照组:0.15,SD 0.82;P < .001)，显著减轻体重(基本:-2.1,SD 3.3 kg，增强:-3.0,SD 4.1，对照:0.4,SD 2.3;P < .001)与腰围变化相关(基本:-2.0,SD 3.5 cm，增强:-3.2,SD 4.7，对照:0.5,SD 3.0; P < .001) and waist-to-height ratio (basic: –0.01, SD 0.02, enhanced: –0.02, SD 0.03, control: 0.0, SD 0.02; P < .001), but no differences were observed between the basic and enhanced groups. The addition of personalized e-feedback and contact provided limited additional benefits compared with the basic program. Conclusions: A commercial Web-based weight-loss program can be efficacious across a range of weight-related outcomes and lifestyle behaviors and achieve clinically important weight loss. Although the provision of additional personalized feedback did not facilitate greater weight loss after 12 weeks, the impact of superior participant retention on longer-term outcomes requires further study. Further research is required to determine the optimal mix of program features that lead to the biggest treatment impact over time. Trial Registration: Australian New Zealand Clinical Trials Registry (ANZCTR): 12610000197033; http://www.anzctr.org.au/trial_view.aspx?id=335159 (Archived by WebCite at http://www.webcitation.org/66Wq0Yb7U) %M 22555246 %R 10.2196/jmir.1980 %U //www.mybigtv.com/2012/2/e57/ %U https://doi.org/10.2196/jmir.1980 %U http://www.ncbi.nlm.nih.gov/pubmed/22555246