杂志文章Gunther Eysenbach对基于网络的手部卫生干预的评价:探索性随机对照试验%A Yardley,Lucy %A Miller,Sascha %A Schlotz,Wolff %A Little,Paul %+南安普顿大学人类和社会科学学院心理学术单位，SO17 1BJ，英国，44 2380 59 4581,L.Yardley@soton.ac.uk %K健康促进%K人类流感%K洗手%K随机对照试验%D 2011 %7 09.12.2011 %9原创论文%J J医学互联网Res %G英语%X背景:洗手被认为是预防呼吸道感染传播的潜在重要行为，特别是在大流行期间。目的:本研究的目的是评估基于网络的干预是否可以鼓励更频繁地在家洗手，并检查结果的潜在中介和调节因素，作为PRIMIT试验(基于网站的感染控制干预的初级保健试验，以修改流感样疾病和呼吸道感染传播)中测试干预对感染率影响的必要的第一步。方法:在一项平行组实用主义探索性试验设计中，通过初级保健招募的517名非盲成人被自动随机分配到一个全自动干预组(包括4次定制的激励信息和自我调节支持(n = 324)或一个无干预对照组(n = 179;比2:1)。在4周(干预后;所有参与者)，以及在12周时。结果:干预组患儿4周洗手率高于对照组(平均4.40,n = 285;平均4.04,n = 157;P < .001, Cohen d = 0.42)，并在12周时保持较高水平(均值4.45,n = 282，均值4.12,n = 154; P < .001, Cohen d = 0.34). Hand-washing intentions and positive attitudes toward hand-washing increased more from baseline to 4 weeks in the intervention group than in the control group. Mediation analyses revealed positive indirect effects of the intervention on change in hand-washing via intentions (coefficient = .15, 95% confidence interval [CI], .08–.26) and attitudes (coefficient = 0.16, 95% CI, .09–.26). Moderator analyses confirmed that the intervention was similarly effective for men and women, those of higher and lower socioeconomic status, and those with higher and lower levels of perceived risk. Conclusions: This study provides promising evidence that Web-based interventions could potentially provide an effective method of promoting hand hygiene in the home. Data were collected during the 2010 influenza pandemic, when participants in both groups had already been exposed to extensive publicity about the need for hand hygiene, suggesting that our intervention could add to existing public health campaigns. However, further research is required to determine the effects of the intervention on actual infection rates. Trial: International Standard Randomized Controlled Trial Number (ISRCTN): 75058295; http://www.controlled-trials.com/ISRCTN75058295 (Archived by WebCite at http://www.webcitation.org/62KSbkNmm) %M 22155673 %R 10.2196/jmir.1963 %U //www.mybigtv.com/2011/4/e107/ %U https://doi.org/10.2196/jmir.1963 %U http://www.ncbi.nlm.nih.gov/pubmed/22155673