e - health干预对药物依从性的影响:文献系统综述%A Linn,Annemiek J %A Vervloet,Marcia %A van Dijk,Liset %A Smit,Edith G %A van Weert,Julia CM %+荷兰卫生服务研究所，邮政信箱1568，乌得勒支，3500 BN，荷兰，31 30 2729713,M.Vervloet@nivel.nl %K互联网干预%K药物依从性%K依从性%K系统综述%K定制%K eHealth %K效果%K RCT %D 2011 %7 05.12.2011 %9综述%J J医学互联网Res %G英文%X背景:由于药物不依从性被认为是一个重要的健康风险，已经开发了许多改善依从性的干预措施。在过去十年中，使用基于互联网的干预措施来改善药物依从性的情况迅速增加。互联网干预具有根据患者的需求和情况定制干预措施的潜在优势。目的:本系统综述的主要目的是调查有针对性的网络干预在提高药物依从性方面是有效的。方法:我们按照Cochrane协作网的指南，在PubMed、psyinfo、EMBASE、CINAHL、Communication abstrals进行综合文献检索。随机对照试验和临床对照试验的方法学质量和测量依从性的方法由两位研究人员独立审查。结果:共有13篇研究符合纳入标准。所有这些互联网干预措施显然都使用了中等或高度复杂的计算机定制方法。 Data synthesis revealed that there is evidence for the effectiveness of Internet interventions in improving medication adherence: 5 studies (3 high-quality studies and 2 low-quality studies) showed a significant effect on adherence; 6 other studies (4 high-quality studies and 2 low-quality studies) reported a moderate effect on adherence; and 2 studies (1 high-quality study and 1 low-quality study) showed no effect on patients’ adherence. However, most studies used self-reported measurements to assess adherence, which is generally perceived as a low-quality measurement. In addition, we did not find a clear relationship between the quality of the studies or the level of sophistication of message tailoring and the effectiveness of the intervention. This might be explained by the great difference in study designs and the way of measuring adherence, which makes results difficult to compare. There was also large variation in the measured interval between baseline and follow-up measurements. Conclusion: This review shows promising results on the effectiveness of Internet interventions to enhance patients’ adherence to prescribed long-term medications. Although there is evidence according to the data synthesis, the results must be interpreted with caution due to low-quality adherence measurements. Future studies using high-quality measurements to assess medication adherence are recommended to establish more robust evidence for the effectiveness of eHealth interventions on medication adherence. %M 22138112 %R 10.2196/jmir.1738 %U //www.mybigtv.com/2011/4/e103/ %U https://doi.org/10.2196/jmir.1738 %U http://www.ncbi.nlm.nih.gov/pubmed/22138112