@文章{信息:doi/10.2196/18946,作者=“程,超和何,彩虹田鸿和郭,燕和朱,孟婷和杨,魏雄和李,怡然和刘,振国和卓,舒玉和梁,齐和陈,正红和曾,玉和杨,贾丽和张,战飞和张,徐和门罗,阿莉扎和杨,赛青”,标题=“移动健康支持的综合干预模型(CIMmH)改善食管癌患者食管癌切除术后生活质量的开发与可行性:前瞻性、单臂、非随机试点研究”,期刊=“J Med Internet Res”,年=“2020”,月=“8”,日=“18”,卷=“22”,数=“8”,页数=“e18946”,关键词=“食管癌;生活质量;营养;体育锻炼;心理支持;移动健康;背景:食管癌患者在食管癌切除术后,由于营养不良、缺乏体育锻炼和心理症状,常出现临床相关的生活质量(QOL)下降。目的:本研究旨在评估移动医疗系统(CIMmH)对食管癌患者食管癌切除术后综合干预模式的可行性、安全性和有效性。方法:20例接受改良McKeown手术的食管癌患者被邀请参加CIMmH项目,包括在线和离线部分,为期12周。 The participants were assessed before surgery and again at 1 and 3 months after esophagectomy. QOL, depressive symptoms, anxiety, stress, nutrition, and physical fitness were measured. Results: Of the 20 patients, 16 (80{\%}) completed the program. One month after esophagectomy, patients showed significant deterioration in overall QOL (P=.02), eating (P=.005), reflux (P=.04), and trouble with talking (P<.001). At the 3-month follow-up, except for pain (P=.02), difficulty with eating (P=.03), dry mouth (P=.04), and trouble with talking (P=.003), all other QOL dimensions returned to the preoperative level. There were significant reductions in weight (P<.001) and BMI (P=.02) throughout the study, and no significant changes were observed for physical fitness measured by change in the 6-minute walk distance between baseline and the 1-month follow-up (P=.22) or between baseline and the 3-month follow-up (P=.52). Depressive symptoms significantly increased 1 month after surgery (P<.001), while other psychological measures did not show relevant changes. Although there were declines in many measures 1 month after surgery, these were much improved at the 3-month follow-up, and the recovery was more profound and faster than with traditional rehabilitation programs. Conclusions: The CIMmH was feasible and safe and demonstrated encouraging efficacy testing with a control group for enhancing recovery after surgery among patients with esophageal cancer in China. Trial Registration: Chinese Clinical Trial Registry (ChiCTR-IPR-1800019900); http://www.chictr.org.cn/showprojen.aspx?proj=32811. ", issn="1438-8871", doi="10.2196/18946", url="//www.mybigtv.com/2020/8/e18946/", url="https://doi.org/10.2196/18946", url="http://www.ncbi.nlm.nih.gov/pubmed/32808933" }
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