@文章{信息:doi/10.2196/23273，作者=“吴，琼，黄，依文，辽，子君，范·维索芬，米歇尔·海伦娜，王，魏，张艳峰”，标题=“微信在中国湖祝县改善纯母乳喂养的有效性:随机对照试验”，期刊=“J医学互联网研究”，年=“2020”，月=“12”，日=“3”，卷=“22”，数=“12”，页=“e23273”，关键词=“母乳喂养;纯母乳喂养;微信;移动健康;背景:母乳喂养对婴儿和母亲的好处已经得到了广泛的认可。然而，中国的纯母乳喂养率很低，而且还在下降。移动技术迅速发展;像微信(中国最大的社交网络平台之一)这样的交流应用程序被广泛使用，并有可能方便地改善健康行为。目的:本研究旨在评估使用微信改善母乳喂养实践的有效性。方法:这项两组随机对照试验于2019年5月至2020年4月在中国青海省湖珠县的孕妇中进行。 Pregnant women were eligible to participate if they were aged 18 years or older, were 11 to 37 weeks pregnant with a singleton fetus, had no known illness that could limit breastfeeding after childbirth, used WeChat through their smartphone, and had access to the internet. A total of 344 pregnant women were recruited at baseline, with 170 in the intervention group and 174 in the control group. Women in the intervention group received breastfeeding knowledge and promotion information weekly through a WeChat official account from their third month of pregnancy to 6 months postpartum. The primary outcome of exclusive and predominant breastfeeding rate was measured 0-1 month, 2-3 months, and 4-5 months postpartum. Results: At 0-1 month postpartum, the exclusive breastfeeding rate was significantly higher in the intervention group than that in the control group (81.1{\%} vs 63.3{\%}; odds ratio [OR] 2.75, 95{\%} CI 1.58-4.78; P<.001). Similarly, mothers in the intervention group were more likely to provide predominantly breast milk (OR 2.77, 95{\%} CI 1.55-4.96; P<.001) and less likely to give dairy products to their children (OR 0.40, 95{\%} CI 0.21-0.75; P=.005). There was no statistically significant difference for exclusive breastfeeding rate 2-3 months (P=.09) and 4-5 months postpartum (P=.27), though more children in the intervention group were exclusively breastfed than those in the control group 2-3 months postpartum (intervention: 111/152, 73.0{\%}; control: 96/152, 63.2{\%}) and 4-5 months postpartum(intervention: 50/108, 46.3{\%}; control: 46/109, 42.2{\%}). Conclusions: This study is the first effort to promote exclusive breastfeeding through WeChat in China, which proved to be an effective method of promoting exclusive breastfeeding in early life. WeChat health education can be used in addition to local breastfeeding promotion programs. Trial Registration: Chinese Clinical Trial Registry ChiCTR1800017364; http://www.chictr.org.cn/showproj.aspx?proj=29325 International Registered Report Identifier (IRRID): RR2-10.1186/s12889-019-7676-2 ", issn="1438-8871", doi="10.2196/23273", url="//www.mybigtv.com/2020/12/e23273", url="https://doi.org/10.2196/23273", url="http://www.ncbi.nlm.nih.gov/pubmed/33270026" }