@文章{信息:doi/10.2196/13609，作者="Mohr, David C和Schueller, Stephen M和Tomasino, Kathryn Noth和Kaiser, Susan M和Alam, Nameyeh和Karr, Chris和Vergara, Jessica L和Gray, Elizabeth L和Kwasny, Mary J和Lattie, Emily G"，标题=" IntelliCare平台上指导和接受应用程序推荐对抑郁、焦虑和参与度的影响比较:析因随机对照试验”，期刊=“J Med Internet Res”，年=“2019”，月=“8”，日=“28”，卷=“21”，数=“8”，页数=“e13609”，关键词=“抑郁症;焦虑;移动健康;IntelliCare是一个模块化平台，包括12个针对常见心理健康问题的特定心理策略的简单应用程序。目的:本研究旨在研究保持IntelliCare平台参与度的两种方法，指导和每周收到尝试不同应用程序的建议对抑郁、焦虑和应用程序使用的影响。方法:共有301名患有抑郁症或焦虑症的参与者被随机分配到4个治疗方案中的1个，持续8周，治疗后随访6个月。试验采用了2X2析因设计(指导vs自我指导治疗，每周应用推荐vs无推荐)来比较用户粘性指标。结果:治疗期间最后一次使用任何应用程序的中位时间为56天(四分位数范围54-57)，治疗后继续使用应用程序的中位时间为92天，有253名参与者(84.0{\%}，253/301)。每周收到的建议导致治疗期间应用程序使用次数显著增加(总体中位数=216; P=.04) but only marginal effects for time to last use (P=.06) and number of app downloads (P=.08). Coaching resulted in significantly more app downloads (P<.001), but there were no significant effects for time to last download or number of app sessions (P=.36) or time to last download (P=.08). Participants showed significant reductions in the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) across all treatment arms (P s<.001). Coached treatment led to larger GAD-7 reductions than those observed for self-guided treatment (P=.03), but the effects for the PHQ-9 did not reach significance (P=.06). Significant interaction was observed between receiving recommendations and time for the PHQ-9 (P=.04), but there were no significant effects for GAD-7 (P=.58). Conclusions: IntelliCare produced strong engagement with apps across all treatment arms. Coaching was associated with stronger anxiety outcomes, and receipt of recommendations enhanced depression outcomes. Trial Registration: ClinicalTrials.gov NCT02801877; https://clinicaltrials.gov/ct2/show/NCT02801877 ", issn="1438-8871", doi="10.2196/13609", url="//www.mybigtv.com/2019/8/e13609/", url="https://doi.org/10.2196/13609", url="http://www.ncbi.nlm.nih.gov/pubmed/31464192" }