@Article{信息:doi 10.2196 / / jmir。9464，作者="Jacobi, Corinna和H{\"u}tter, Kristian和V{\"o}lker, Ulrike和M{\"o}bius, Katharina和Richter, Robert和Trockel, Mickey和Jones Bell, Megan和Lock, James和Taylor, C Barr"，标题="基于父母的神经性厌食症指导性预防的有效性:随机对照试验"，期刊="J Med Internet Res"，年="2018"，月="12"，日="14"，卷="20"，数="12"，页数="e296"，关键词="神经性厌食症;指向性预防;互联网;父母的干预;背景:网络预防干预可以降低年轻高危女性暴食症和暴食障碍的风险和发生率。但对神经性厌食症(AN)核心症状的特异性作用较弱。目的:本研究的主要目的是评估一个指征的、基于父母的、基于网络的预防项目Eltern als Therapeuten (E@T)在减少an的危险因素和症状方面的效果。方法:选取11 - 17岁的女童进行AN的危险因素和早期症状筛查。然后，高危家庭被随机分配到E@T或仅作为评估对照条件。 Assessments took place at pre- and postintervention (6 weeks later) and at 6- and 12-month follow-up (FU). Results: A total of 12,377 screening questionnaires were handed out in 86 German schools, and 3941 including consent returned. Overall, 477 (447/3941, 12.10{\%}) girls were identified as at risk for AN and 256 of those could be contacted. In all, 66 families (66/256, 25.8{\%} of those contacted) were randomized to the E@T or a wait-list control condition, 43 (43/66, 65{\%}) participated in postassessments, and 27 (27/66, 41{\%}) in 12-month FUs. Due to low participation and high dropout rates of parents, recruitment was terminated prematurely. At 12-month FU, girls' expected body weight (EBW) percentage was significantly greater for intervention participants compared with control participants (group by time interaction beta=21.0 [CI 5.81 to 36.13], P=.007; group by time squared interaction beta=−15.5 [CI −26.6 to −4.49], P=.007; estimated Cohen d=0.42]. No other significant effects were found on risk factors and attitudes of disturbed eating. Conclusions: Despite a significant increase in girls' EBW percentage, parental participation and adherence to the intervention were low. Overall, parent-based, indicated prevention for children at risk for AN does not seem very promising, although it might be useful for parents who engage in the intervention. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 18614564; http://www.isrctn.com/ISRCTN18614564 (Archived by WebCite at http://www.webcitation.org/74FTV1EpF). ", issn="1438-8871", doi="10.2196/jmir.9464", url="//www.mybigtv.com/2018/12/e296/", url="https://doi.org/10.2196/jmir.9464", url="http://www.ncbi.nlm.nih.gov/pubmed/30552078" }