@Article{信息:doi 10.2196 / / jmir。5662，作者=“Balestra, Martina和Shaer, Orit和Okerlund, Johanna和Westendorf, Lauren和Ball, Madeleine和Nov, Oded”，标题=“社会注释价:对在线知情同意信念和行为的影响”，期刊=“J Med Internet Res”，年=“2016”，月=“7月”，日=“20”，卷=“18”，数=“7”，页=“e197”，关键词=“同意书;决策支持系统;社会标签系统;知情同意;背景:社交媒体、移动和可穿戴技术以及连接设备极大地扩展了在线进行生物医学研究的机会。然而，与传统的同意程序相比，收集这些数据的电子同意提出了新的挑战。它减少了参与者-研究人员的对话，但为同意审议过程从单独到社会环境提供了机会。在这项研究中，我们建议在同意书中嵌入社会注释，可以帮助潜在参与者以传统同意书无法做到的方式考虑研究及其背后的组织。此外，我们研究了评论的效价对潜在参与者的信念和行为的作用。 Objective: This study focuses specifically on the influence of annotations' valence on participants' perceptions and behaviors surrounding online consent for biomedical research. We hope to shed light on how social annotation can be incorporated into digitally mediated consent forms responsibly and effectively. Methods: In this controlled between-subjects experiment, participants were presented with an online consent form for a personal genomics study that contained social annotations embedded in its margins. Individuals were randomly assigned to view the consent form with positive-, negative-, or mixed-valence comments beside the text of the consent form. We compared participants' perceptions of being informed and having understood the material, their trust in the organization seeking the consent, and their actual consent across conditions. Results: We find that comment valence has a marginally significant main effect on participants' perception of being informed (F2=2.40, P=.07); specifically, participants in the positive condition (mean 4.17, SD 0.94) felt less informed than those in the mixed condition (mean 4.50, SD 0.69, P=.09). Comment valence also had a marginal main effect on the extent to which participants reported trusting the organization (F2=2.566, P=.08). Participants in the negative condition (mean 3.59, SD 1.14) were marginally less trusting than participants exposed to the positive condition (mean 4.02, SD 0.90, P=.06). Finally, we found that consent rate did not differ across comment valence conditions; however, participants who spent less time studying the consent form were more likely to consent when they were exposed to positive-valence comments. Conclusions: This work explores the effects of adding a computer-mediated social dimension, which inherently contains human emotions and opinions, to the consent deliberation process. We proposed that augmenting the consent deliberation process to incorporate multiple voices can enable individuals to capitalize on the knowledge of others, which brings to light questions, problems, and concerns they may not have considered on their own. We found that consent forms containing positive valence annotations are likely to lead participants to feel less informed and simultaneously more trusting of the organization seeking consent. In certain cases where participants spent little time considering the content of the consent form, participants exposed to positive valence annotations were even more likely to consent to the study. We suggest that these findings represent important considerations for the design of future electronic informed consent mechanisms. ", issn="1438-8871", doi="10.2196/jmir.5662", url="//www.mybigtv.com/2016/7/e197/", url="https://doi.org/10.2196/jmir.5662", url="http://www.ncbi.nlm.nih.gov/pubmed/27439320" }