@Article{信息:doi 10.2196 / / jmir。4396，作者=“Adusumalli, Swarnaseetha and Lee, HueyTyng and Hoi, qize and Koo, Si-Lin and Tan, Iain Beehuat and Ng, Pauline Crystal”，标题=“基于web的消费者评论作为药物性能资源的评估”，期刊=“J Med Internet Res”，年=“2015”，月=“8”，日=“28”，卷=“17”，数=“8”，页=“e211”，关键词=“消费者药物评论;在线药物评级;中央社报道;背景:一些健康网站为消费者提供了一个发布药物评级和评论的公共论坛。与临床试验和发表的文献不同，药物评论很容易获得和理解。由于公众越来越多地使用互联网作为医疗信息的来源，了解这些信息是否可靠是很重要的。目的:我们的目的是研究基于网络的消费者药物评级和评论是否可以用作比较药物性能的一种资源。方法:我们分析了来自健康网站WebMD的103,411条消费者对615种用于治疗249种疾病的药物的评论。统计分析确定了来自24种情况的427个药物对，其中两种药物治疗相同的情况有显著和实质性的满意度评分差异(web评分和P<.01之间至少有0.5点的差异)。 PubMed and Google Scholar were searched for publications that were assessed for concordance with findings online. Results: Scientific literature was found for 77 out of the 427 drug pairs and compared to findings online. Nearly two-thirds (48/77, 62{\%}) of the online drug trends with at least a half-point difference in online ratings were supported by published literature (P=.02). For a 1-point online rating difference, the concordance rate increased to 68{\%} (15/22) (P=.07). The discrepancies between scientific literature and findings online were further examined to obtain more insights into the usability of Web-based consumer-generated reviews. We discovered that (1) drugs with FDA black box warnings or used off-label were rated poorly in Web-based reviews, (2) drugs with addictive properties were rated higher than their counterparts in Web-based reviews, and (3) second-line or alternative drugs were rated higher. In addition, Web-based ratings indicated drug delivery problems. If FDA black box warning labels are used to resolve disagreements between publications and online trends, the concordance rate increases to 71{\%} (55/77) (P<.001) for a half-point rating difference and 82{\%} (18/22) for a 1-point rating difference (P=.002). Our results suggest that Web-based reviews can be used to inform patients' drug choices, with certain caveats. Conclusions: Web-based reviews can be viewed as an orthogonal source of information for consumers, physicians, and drug manufacturers to assess the performance of a drug. However, one should be cautious to rely solely on consumer reviews as ratings can be strongly influenced by the consumer experience. ", issn="1438-8871", doi="10.2196/jmir.4396", url="//www.mybigtv.com/2015/8/e211/", url="https://doi.org/10.2196/jmir.4396", url="http://www.ncbi.nlm.nih.gov/pubmed/26319108" }