@Article{信息:doi 10.2196 / / jmir。3720,作者=“Hoen, Anne G和Hladish, Thomas J和Eggo, Rosalind M和Lenczner, Michael和Brownstein, John S和Meyers, Lauren Ancel”,标题=“城市社区结构的流行波动力学:一个大网络中疾病传播的理论表征”,期刊=“J Med Internet Res”,年=“2015”,月=“july”,日=“08”,卷=“17”,数=“7”,页=“e169”,关键词=“传染病;流行;背景:传染病流行期间的多波传播是一项重大的公共卫生挑战,但对流行病卷土重来的生态和行为驱动因素了解甚少。从理论上讲,随着疾病从一个社区传播到另一个社区,人口内部的社区结构——聚集成高度相互联系和松散相互联系的社会群体——可能导致间歇性爆发。然而,由于环境条件和人类行为的时间变化以及估计大规模接触模式的困难,这种解释在很大程度上被忽视了。目的:目的是表征能够产生具有多重波结构的模拟流行病的自然产生的人类接触模式。方法:我们使用公共Wi-Fi互联网系统用户之间近端物理接触的广泛数据集来评估经验城市接触网络的流行病学意义。我们描述了网络的模块化(社区结构),然后在基于渗透的传染病在网络上传播的模型下估计了流行动态。我们使用一种新的度量方法将模拟流行病分类为多波流行病,并确定了对网络产生多波流行病能力至关重要的网络结构。 Results: We identified robust community structure in a large, empirical urban contact network from which multiwave epidemics may emerge naturally. This pattern was fueled by a special kind of insularity in which locally popular individuals were not the ones forging contacts with more distant social groups. Conclusions: Our results suggest that ordinary contact patterns can produce multiwave epidemics at the scale of a single urban area without the temporal shifts that are usually assumed to be responsible. Understanding the role of community structure in epidemic dynamics allows officials to anticipate epidemic resurgence without having to forecast future changes in hosts, pathogens, or the environment. ", issn="1438-8871", doi="10.2196/jmir.3720", url="//www.mybigtv.com/2015/7/e169/", url="https://doi.org/10.2196/jmir.3720", url="http://www.ncbi.nlm.nih.gov/pubmed/26156032" }
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