@Article{信息:doi 10.2196 / / jmir。3203，作者=“Zheluk, Andrey and Quinn, Casey and Meylakhs, Peter”，标题=“俄罗斯联邦的互联网搜索和Krokodil:一项信息监视研究”，期刊=“J Med Internet Res”，年=“2014”，月=“Sep”，日=“18”，卷=“16”，数=“9”，页=“e212”，关键词=“俄罗斯;搜索引擎;监测;受控物质;设计师药物;背景:Krokodil是用含可待因的药物(CCM)在国内制备的廉价可注射非法药物的非正式术语。krokodil的制备方法可能产生去吗啡以及引起广泛组织坏死的有毒反应物。2004年，俄罗斯首次证实使用krokodil。2012年，俄罗斯以外的西欧和美国开始出现与鳄鱼有关的注射伤害报告。 Objective: This exploratory study had two main objectives: (1) to determine if Internet search patterns could detect regularities in behavioral responses to Russian CCM policy at the population level, and (2) to determine if complementary data sources could explain the regularities we observed. Methods: First, we obtained krokodil-related search pattern data for each Russia subregion (oblast) between 2011 and 2012. Second, we analyzed several complementary data sources included krokodil-related court cases, and related search terms on both Google and Yandex to evaluate the characteristics of terms accompanying krokodil-related search queries. Results: In the 6 months preceding CCM sales restrictions, 21 of Russia's 83 oblasts had search rates higher than the national average (mean) of 16.67 searches per 100,000 population for terms associated with krokodil. In the 6 months following restrictions, mean national searches dropped to 9.65 per 100,000. Further, the number of oblasts recording a higher than average search rate dropped from 30 to 16. Second, we found krokodil-related court appearances were moderately positively correlated (Spearman correlation=.506, P≤.001) with behaviors consistent with an interest in the production and use of krokodil across Russia. Finally, Google Trends and Google and Yandex related terms suggested consistent public interest in the production and use of krokodil as well as for CCM as analgesic medication during the date range covered by this study. Conclusions: Illicit drug use data are generally regarded as difficult to obtain through traditional survey methods. Our analysis suggests it is plausible that Yandex search behavior served as a proxy for patterns of krokodil production and use during the date range we investigated. More generally, this study demonstrates the application of novel methods recently used by policy makers to both monitor illicit drug use and influence drug policy decision making. ", issn="1438-8871", doi="10.2196/jmir.3203", url="//www.mybigtv.com/2014/9/e212/", url="https://doi.org/10.2196/jmir.3203", url="http://www.ncbi.nlm.nih.gov/pubmed/25236385" }