@Article{信息:doi 10.2196 / / jmir。2647，作者=“尼古拉斯，安吉拉和贝利，朱莉娅V和史蒂文森，菲奥娜和默里，伊丽莎白”，标题=“Sexunzipped试验:年轻人参与在线随机对照试验的观点”，期刊=“J医学互联网Res”，年=“2013”，月=“12月”，日=“12”，卷=“15”，数字=“12”，页=“e276”，关键词=“互联网;随机对照试验;定性研究;结果评估(保健);性的健康;沙眼衣原体”，摘要=“背景:英国年轻人中性传播感染(STIs)的发病率正在增加。由于互联网在年轻人中使用率很高，有可能产生匿名感，而且易于获取，因此可以成为提供性健康信息和促进性健康的适当媒介。在线随机对照试验(rct)越来越多地用于评估在线干预措施，但尽管在线方法有许多优点，但它们也可能与许多问题有关，包括在线干预措施的参与度低、试验保留率低以及对在线自我报告收集的数据有效性的担忧。我们进行了一项在线可行性试验，测试了sexunzip网站对性健康的影响，并将其与纯信息网站进行了比较。 This study reports on a qualitative evaluation of the trial procedures, describing participants' experiences and views of the Sexunzipped online trial including methods of recruitment, incentives, methods of contact, and sexual health outcome measurement. Objective: Our goal was to determine participants' views of the acceptability and validity of the online trial methodology used in the pilot RCT of the Sexunzipped intervention. Methods: We used three qualitative data sources to assess the acceptability and validity of the online pilot RCT methodology: (1) individual interviews with 22 participants from the pilot RCT, (2) 133 emails received by the trial coordinator from trial participants, and (3) 217 free-text comments from the baseline and follow-up questionnaires. Interviews were audio-recorded and transcribed verbatim. An iterative, thematic analysis of all three data sources was conducted to identify common themes related to the acceptability and feasibility of the online trial methodology. Results: Interview participants found the trial design, including online recruitment via Facebook, online registration, email communication with the researchers, and online completion of sexual health questionnaires to be highly acceptable and preferable to traditional methods. Incentives might assist in recruiting those who would not otherwise participate. Participants generally enjoyed taking part in sexual health research online and found the questionnaire itself thought-provoking. Completing the sexual health questionnaires online encouraged honesty in responding that might not be achieved with other methods. The majority of interview participants also thought that receiving and returning a urine sample for chlamydia testing via post was acceptable. Conclusions: These findings provide strong support for the use of online research methods for sexual health research, emphasizing the importance of careful planning and execution of all trial procedures including recruitment, respondent validation, trial related communication, and methods to maximize follow-up. Our findings suggest that sexual health outcome measurement might encourage reflection on current behavior, sometimes leading to behavior change. Trial Registration: International Standard Randomized Controlled Trial Number (ISRCTN): 55651027; http://www.controlled-trials.com/isrctn/pf/55651027 (Archived by WebCite at http://www.webcitation.org/6LbkxdPKf). ", issn="14388871", doi="10.2196/jmir.2647", url="//www.mybigtv.com/2013/12/e276/", url="https://doi.org/10.2196/jmir.2647", url="http://www.ncbi.nlm.nih.gov/pubmed/24334198" }