@Article{信息:doi 10.2196 / / jmir。1855年，作者=“Cohen, Ellyn和Belkora, Jeff和Tyler, Joanne和Schreiner, Joan和Deering, Mary Jo和Grama, Lakshmi和Duggan, Brenda和Illi, Julie和peggan, Julia和Anand, Aprajita和Teng, Alexandra和McCreary, Erin和Moore, Dan和Tripathy, Debu和Hogarth, Michael和Lieberman, Morton和Park, John和Esserman, Laura”，标题=“乳腺癌在线临床试验匹配网站的采用，可接受性和准确性”，期刊=“J Med Internet Res”，年="2012"，月=" 7月"，日="11"，卷="14"，数="4"，页数="e97"，关键词="乳腺癌;临床试验;背景:只有不到5%的乳腺癌患者参与了临床试验。为了提高患者的意识和获得试验的机会，我们创建了BreastCancerTrials.org，一个临床试验匹配网站。BreastCancerTrials.org根据患者自我报告的乳腺癌病史将他们与试验相匹配。它还提供了一个消息平台，患者可以通过该平台自我介绍参与研究的网站。目的:评估研究地点的采用率、患者的可接受性以及患者向BreastCancerTrials.org提供信息的准确性。方法:我们联系了北加州的13个研究机构，在BreastCancerTrials.org上列出了他们的试验。 For adoption, we examined the willingness of contacted research sites to collaborate with BreastCancerTrials.org. For acceptability, we analyzed usage statistics of visitors who completed the BreastCancerTrials.org health history questionnaire in the first 14 months after launch and surveyed users who visited the website during its first year about their experience. For accuracy, we compared the self-reported health history of 20 patients against their medical records. The health history questionnaire was divided into four sections: About Me, personal information including date of birth and sex; My Health as of Today, current status including cancer stage, menopausal status, and sites with evidence of disease; My Cancer, diagnostic information such as hormone and human epidermal growth factor receptor 2 status; and My Treatment, an itemized record of past treatment including responses to therapy. Results: A total of 12 sites contributed 55 trials. Regarding acceptability, 733 visitors registered on the website; 428 reported their health history; and 407 matched to at least one trial. Of 375 patients who were sent a survey, 75 responded (20{\%}); 23 of the 75 (31{\%}) contacted a research site, 12 of the 23 (52{\%}) were eligible for a trial, and 5 of the 12 (42{\%}) reported enrolling. As for accuracy, 20 clinic visitors reported 1456 health history items, 1324 of which matched their clinic record (90.93{\%}). Conclusions: BreastCancerTrials.org was adopted by research sites. Patients found it acceptable and were able to provide accurate information for trial matching. Based on our findings, we launched an upgraded version of BreastCancerTrials.org as a national service in October 2008. ", issn="1438-8871", doi="10.2196/jmir.1855", url="//www.mybigtv.com/2012/4/e97/", url="https://doi.org/10.2196/jmir.1855", url="http://www.ncbi.nlm.nih.gov/pubmed/22784878" }