@Article{信息:doi 10.2196 / / jmir。1980，作者=“Collins, Clare E和Morgan, Philip J和Jones, Penelope和Fletcher, Kate和Martin, Julia和Aguiar, Elroy J和Lucas, Ashlee和Neve, Melinda J和Callister, Robin”，标题=“超重和肥胖成人的12周商业网络减肥计划:比较基本特征和增强特征的随机对照试验”，期刊=“J医学互联网研究”，年=“2012”，月=“Apr”，日=“25”，卷=“14”，数=“2”，页数=“e57”，关键词=“干预;减肥;基于web的干预;随机对照试验;减少饮食;背景:基于网络的减肥项目的开发和使用正在迅速增加，但很少使用随机对照试验(rct)对其进行评估。有趣的是，大多数尝试减肥的人都使用商业上可获得的项目，但商业项目很少被独立或严格地评估。目的:比较标准的基于网络的商业减肥计划(基本)与该网络计划的增强版(增强版)在超重和肥胖成人的体重结果方面提供额外的个性化电子反馈和提供者联系(对照组)。方法:这项纯基于网络的试验使用了一个封闭的在线用户组，是一种评估者盲法随机对照试验，参与者随机分配到基于社会认知理论的基础或增强的12周基于网络的项目，或以体重指数(BMI)为主要结果的对照组。 Results: We enrolled 309 adults (129/309, 41.8{\%} male, BMI mean 32.3, SD 4 kg/m2) with 84.1{\%} (260/309) retention at 12 weeks. Intention-to-treat analysis showed that both intervention groups reduced their BMI compared with the controls (basic: --0.72, SD 1.1 kg/m2, enhanced: --1.0, SD 1.4, control: 0.15, SD 0.82; P < .001) and lost significant weight (basic: --2.1, SD 3.3 kg, enhanced: --3.0, SD 4.1, control: 0.4, SD 2.3; P < .001) with changes in waist circumference (basic: --2.0, SD 3.5 cm, enhanced: --3.2, SD 4.7, control: 0.5, SD 3.0; P < .001) and waist-to-height ratio (basic: --0.01, SD 0.02, enhanced: --0.02, SD 0.03, control: 0.0, SD 0.02; P < .001), but no differences were observed between the basic and enhanced groups. The addition of personalized e-feedback and contact provided limited additional benefits compared with the basic program. Conclusions: A commercial Web-based weight-loss program can be efficacious across a range of weight-related outcomes and lifestyle behaviors and achieve clinically important weight loss. Although the provision of additional personalized feedback did not facilitate greater weight loss after 12 weeks, the impact of superior participant retention on longer-term outcomes requires further study. Further research is required to determine the optimal mix of program features that lead to the biggest treatment impact over time. Trial Registration: Australian New Zealand Clinical Trials Registry (ANZCTR): 12610000197033; http://www.anzctr.org.au/trial{\_}view.aspx?id=335159 (Archived by WebCite at http://www.webcitation.org/66Wq0Yb7U) ", issn="1438-8871", doi="10.2196/jmir.1980", url="//www.mybigtv.com/2012/2/e57/", url="https://doi.org/10.2196/jmir.1980", url="http://www.ncbi.nlm.nih.gov/pubmed/22555246" }